Insights into Vitamin E Therapy

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmacology".

Deadline for manuscript submissions: 20 July 2024 | Viewed by 442

Special Issue Editors

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Guest Editor
Institute of Nutritional Sciences and Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Friedrich Schiller University Jena, 07743 Jena, Germany
Interests: vitamin E in health and disease; cardiometabolic diseases; inflammation; vitamin E metabolism; long-chain metabolites of vitamin E

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Guest Editor
Institute of Nutritional Science, Friedrich Schiller University Jena, 07743 Jena, Germany
Interests: vitamins; inflammation; cardiometabolic diseases; skin diseases; macrophages
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In 2022, scientists around the world celebrated the centennial anniversary of the discovery of the essentiality of vitamin E. Since then, many studies highlighted the importance of vitamin E for the maintenance of health and prevention of diseases—facts that received a great deal of attention from scientists and the public.

Scientific research on vitamin E is still an exciting and important issue. Although it has long been known as an antioxidant and radical scavenger, vitamin E is also proposed to act via non-antioxidant modes which include the regulation of gene expression, modulation of gene activity at the posttranslational level, as well as inhibition of cell proliferation, platelet aggregation, monocyte adhesion and several more. Next, metabolites of vitamin E have also been proposed to be bioactive regulatory molecules that may mediate the function of vitamin E in part. The elucidation of the molecular mechanisms and the physiological significance of these non-antioxidant functions of vitamin E and its metabolites is the subject of current and future research.

This Special Issue of Pharmaceuticals on “Insights into Vitamin E Therapy” will display our current knowledge on the use of vitamin E for both maintaining health and preventing diseases by including articles on both experimental and clinical studies as well as reviews focused on the most recent advances in research on the function of vitamin E and its derivatives in medicine. The major focus will be on vitamin E and its effects on different diseases, including studies concerning their pathophysiological and molecular mechanisms. Special attention will be also paid to the synthesis of vitamin E, vitamin derivatives and metabolites, as well as their analytics.

With the aim of providing a dedicated forum open to all scientists engaged in this interdisciplinary field of research, we particularly welcome contributions dealing with the following topics:

  • Beneficial effects of vitamin E and its derivates as therapeutics for the maintenance of health and prevention of diseases;
  • Synthesis and analysis of vitamin E forms, their derivatives and metabolites, and of vitamin-related compounds;
  • Formulations of vitamin E and its derivatives for different medical applications;
  • Experimental studies and clinical trials with vitamin E and its derivatives for the treatment of different disorders;
  • Recommended dietary intake and allowance, overdosage and safety of vitamin E;
  • Molecular modes of action of the different vitamin E forms, their derivatives and metabolites, and of vitamin-related compounds;
  • Historical views on clinical trials with vitamin E and its derivatives;
  • Future perspectives of vitamin E research;
  • Genetic factors associated with the response to vitamin E.

We are looking forward to receiving numerous articles on these and related topics.

Prof. Dr. Stefan Lorkowski
Dr. Maria Wallert
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • vitamin E synthesis
  • non-communicable diseases
  • cardiovascular diseases
  • cardiometabolic diseases
  • fatty liver diseases
  • skin diseases
  • inflammation
  • AVED

Published Papers

This special issue is now open for submission.
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