Pharmacotherapy of Neurodegeneration Disorders
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmacology".
Deadline for manuscript submissions: 30 April 2024 | Viewed by 297
Special Issue Editors
Interests: neuroprotection; neuroinflammation; oxidative stress; antioxidant activity; MAO inhibition; hepatotoxicity; neurotoxicity; biotransformation
Special Issues, Collections and Topics in MDPI journals
Interests: medicinal chemistry; pharmaceutical chemistry; organic synthesis; heterocycles; drug design and discovery; synthesis and structure-activity relationships of biologically active compounds (small molecules); drug metabolism; pharmacokinetics; pharmacodynamics; drug analysis; chromatography
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
A significant increase in the ageing of populations worldwide is especially prevalent in recent decades, with age-related rates steadily increasing. The progressive degeneration and/or death of neuronal cells, resulting in the manifestation of motor (ataxia) and mental disorders (dementia), is linked to a number of neurodegenerative diseases, characterized by the loss of neurons in certain areas of the brain. The current therapeutic strategies in neurodegenerative diseases are mainly aimed at influencing various symptoms, where increasing interest is paid to the key role of oxidative stress and inflammatory processes in the pathogenesis of neurodegenerative diseases. In this relationship, the isolation or synthesis of various biologically active molecules with potential anti-inflammatory and antioxidant effects would expand approaches for the therapy of these diseases beyond conventional treatment, which is accompanied by the manifestation of a number of adverse drug reactions. In addition, the search and the design of new chemically available multitarget agents will add to the search for contemporaneous strategies in neurodegenerative tratment.
Prof. Dr. Magdalena Kondeva-Burdina
Prof. Dr. Maya Georgieva
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neurodegeneration
- inflammation
- oxidative stress
- neuroprotection
- new biologically active molecules
- heterocycles
- synthesis
- in silico drug design
- pyrrole
- MW-assisted synthesis
- pharmaceutical chemistry
