Pharmacology and Toxicology of Opioids

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmacology".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 679

Special Issue Editors


E-Mail Website
Guest Editor
1. 1H-TOXRUN—One Health Toxicology Research Unit, University Institute of Health Sciences—CESPU (IUCS-CESPU), 4585-116 Gandra, Portugal
2. UCIBIO-REQUIMTE—Applied Molecular Biosciences Unit-Network of Chemistry and Technology, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal
Interests: opioid pharmacology; prescription opioids; toxicity assays; toxicity mechanisms; in vivo models; in vitro models

E-Mail Website
Guest Editor
1. 1H-TOXRUN—One Health Toxicology Research Unit, University Institute of Health Sciences—CESPU (IUCS-CESPU), 4585-116 Gandra, Portugal 2. UCIBIO-REQUIMTE—Applied Molecular Biosciences Unit-Network of Chemistry and Technology, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal
Interests: toxicology; opioid pharmacology; opioid pharmacokinetics; opioid pharmacodynamics; toxicity biomarkers; adverse outcome pathways; toxicity screening; in vitro assays; in vivo assays

E-Mail Website
Guest Editor
1. 1H-TOXRUN—One Health Toxicology Research Unit, University Institute of Health Sciences—CESPU (IUCS-CESPU), 4585-116 Gandra, Portugal
2. UCIBIO-REQUIMTE—Applied Molecular Biosciences Unit of Network of Chemistry and Technology, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal
3. Department of Public Health and Forensic Sciences, and Medical Education, Faculty of Medicine, University of Porto, 4099-002 Porto, Portugal
4. FOREN—Forensic Science Experts, 4200-604 Porto, Portugal
Interests: toxicology; psychoactive substances; forensic sciences; drugs; opioids; biomedical research; scientometrics; scientific medical writing; pedagogical innovation; real-world evidence
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Special Issue Information

Dear Colleagues,

Opioids are a broad group of drugs that include illegal drugs and medicines. In the pharmacological context, opioids are currently used as a gold standard for the treatment of moderate to severe pain. Pain is a complex and subjective experience, and is a symptom associated with several pathologies, many of which are extremely frequent, leading to the widespread consumption of opioids. Despite their high analgesic efficiency, the incidence of side effects and adverse reactions, poisoning cases, including fatal intoxications, as well as cases of addiction, are growing along with the increase in their use and misuse. In fact, opioid consumption is leading to an opioid epidemic and a public health crisis. 

In this context, it is important to broaden the knowledge of opioid pharmacology and toxicity mechanisms to improve their therapeutic efficacy and lower the rate of adverse effects, ultimately improving the quality of life of many patients. Furthermore, it is also important to understand and decrease the potential for opioid dependence, besides searching for new analgesic opioids. Therefore, in this Special Issue, authors are invited to submit original papers, review, communications, perspectives and opinion articles on all relevant aspects of opioid pharmacology and toxicology. 

Research areas may include the following:

  • In vitro and in vivo studies on opioid toxicity;
  • In vitro and in vivo studies on opioid structure–activity;
  • Pharmacokinetic and pharmacodynamic studies;
  • Behavioral studies;
  • New advancements in opioid pharmacology, including (but not limited to) new opioid drug candidates;
  • New opioid quantification methodologies

Dr. Juliana Faria
Dr. Joana Barbosa
Prof. Dr. Ricardo Dinis-Oliveira
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • opioid toxicity
  • opioid pharmacodynamics
  • opioid pharmacokinetics
  • opioid pharmacogenetics
  • prescription opioids
  • toxicity assays
  • in vivo
  • in vitro
  • abuse
  • dependence

Published Papers

This special issue is now open for submission.
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