Cardiovascular Physiology and Haemodynamics: Haemodynamic Optimisation

Dear Colleagues,

It is our great pleasure to present you this Special Issue aimed at providing a comprehensive overview of the latest research achievements, challenges, and recommendations concerning haemodynamic optimisation. As you all know, haemodynamic optimisation includes a series of therapeutic interventions on the cardiovascular system in order to provide an optimal oxygen supply in critical conditions, such as high-risk surgery. Over the past two decades, interest in the concept of pre-, peri-, and post-operative haemodynamic optimisation has grown as a result of the evidence that demonstrate the advantages for patient outcomes. However, there are still a bulk of discordant findings and arising questions which impose the need for a deeper understanding of the underlying mechanisms and factors that influence the success of maintaining cardiovascular function. The papers resulting from this Special Issue will therefore make an important contribution to the understanding of this procedure, whose usefulness in a practical work seems justified. Therefore, original articles based on animal and human investigations, as well as systematic reviews, are more than welcome in this Special Issue. Potential topics include, but are not limited to, the following research areas:

• Myocardial ischemia/reperfusion injury;
• Oxidative stress in cardiovascular diseases;
• Endothelial dysfunction;
• Operative care;
• Fluid replacement.

We look forward to your contributions.

Prof. Dr. Vladimir Jakovljevic
Dr. Nevena Jeremic
Guest Editors

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• cardiovascular system
• haemodynamics
• fluids
• operative care
• oxygen supply