Luminescent Techniques – Effective Tools in the Search for Novel, Biologically Active Agents
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Cross-Field Chemistry".
Deadline for manuscript submissions: closed (28 February 2022) | Viewed by 342
Special Issue Editors
Interests: GPCR; histamine H3 receptors; histamine H4 receptors; orphan GPR18 receptors; molecular modeling
2. Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland
Interests: medicinal chemistry; sigma-1 receptor ligands; histamine H3 receptor ligands; pain management
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Over the past few decades, fluorescent/luminescent techniques have made their way to the top, leaving classical radioligand assays far behind in terms of safety, efficacy, reliability, and accessibility. But what tips the balance is their versatility in being used on both sides of the membrane. It might be either a fluorescent probe used in BRET-based binding studies or a technique that allows for real-time monitoring of specific pathways in response to a ligand. All of them meet the need of current drug development for selective, biased ligands with reduced adverse effects.
In this Special Issue, we invite researchers to literally shed some light on the vast, yet still increasing field of fluorescent/luminescent techniques. Regardless of what side of the membrane you are studying, share your original research with us.
Dr. Kamil Kuder
Dr. Katarzyna Szczepanska
Guest Editors
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Keywords
- fluorescence
- luminescence
- fluorescent probes
- fret
- bret
- signaling pathway
- luminescent assays
- fluorescent assays
- fluorescent ligands
