The Versatility of Curcumin for the Design of Bioactive Compounds
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 176
Special Issue Editor
Interests: medicinal chemistry; natural products; curcumin; drug design; multitarget drug discovery; bioactive compounds; neurodegeneration; cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The polyphenol curcumin, found in Curcuma longa L., is one of the most thoroughly investigated natural products, as documented by the impressive number of studies claiming its efficacy for both the prevention and treatment of a vast number of disorders. This peculiar pleiotropic profile, mainly due to the simultaneous modulation of multiple and structurally unrelated targets, offers promise for addressing complex maladies. This natural compound, regarded as a privileged structure, has primarily been exploited in medicinal chemistry, and various bioactive molecules have been developed.
This Special Issue aims to provide an overview of the latest findings in curcumin and its analogues, focusing on drug design, synthesis, computational studies, mechanisms of action, and formulation. Original articles, short communications, and reviews of studies on this topic are welcome.
Dr. Federica Belluti
Guest Editor
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Keywords
- bioactive compounds
- curcumin
- drug design
- synthesis
- computational study
- formulation: medicinal chemistry
- structure–activity relationship (SAR) study
