Mass Spectrometry Based Omics in Toxicology and Drug-Induced Toxicity Assessment
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".
Deadline for manuscript submissions: 30 April 2024 | Viewed by 152
Special Issue Editor
Interests: pharmaceutical analysis; method development for the determination of bioactive substances in biological fluids; separation methods (GC, HPLC, UPLC); mass spectrometry (TQ, QqToF, orbitrap, ion-trap); synthesis of fluorescent probes; computational chemistry (αb initio, DFT, CASSCF)
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Special Issue Information
Dear Colleagues,
The need for new assessment methodologies in toxicology and in drug-induced toxicity assessment is emerging as a mandate in medicine. Toxicology in the 21st century is moving towards non-animal toxicology methods that enable the high-throughput subclinical detection of a toxicological incident onset, thus enabling the timely and efficient treatment or even prevention of such events. The spectacular progress made thus far in the field of omics has benefited the field of toxicology enormously. In this regard, mass spectrometry has been deemed perhaps the most powerful tool for omics analyses, often in conjunction with advanced chemometrics and statistical methodologies.
In this Special Issue, we are inviting you to contribute novel ideas relating to cohort, sampling, sample pretreatment, instrumental methodologies and instrumentation, and new data treatment approaches and applications thereof in toxicology and drug-induced toxicity assessment.
Prof. Dr. Evagelos Gikas
Guest Editor
Manuscript Submission Information
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Keywords
- new insights in the area of interest
- proteomics, peptidomics, metabolomics/lipidomics but not excluding other omics approaches
- statistical sampling design
- non-evasive methodologies of sample acquisition
- innovative mass spectrometric methodologies
- new methods of statistical data treatment
- applications in the area of toxicology and drug induced toxicity assessment
- imaging applications including DART and MALDI
- microfluidics assisted toxicological methodologies of analysis
- 3D cell metabolomics—organs-on-a-chip metabolomics
