Chemistry of Nucleosides and Nucleotides and Their Analogues
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".
Deadline for manuscript submissions: 31 August 2024 | Viewed by 87
Special Issue Editors
Interests: solid-phase synthesis; chemistry of nucleosides, nucleotides, and oligonucleotides; L-sugars; platinum complexes; heterocycles; bioorganic chemistry
Special Issues, Collections and Topics in MDPI journals
Interests: nucleic acid chemistry and biology; DNA quadruplexes formed by telomers, aptamers, and synthetic G-rich oligonucleotides; chemical-physical characterization of soft interfaces; hybrid interfaces; therapeutics; diagnostics
Special Issues, Collections and Topics in MDPI journals
Interests: peptide nucleic acid; G-quadruplex; delivery; solid-phase synthesis; small molecule-DNA interactions
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The importance of nucleosides and nucleotides in medicinal chemistry is widely recognized. In recent years, there has been a growing interest in the synthesis of modified compounds and analogues, particularly considering the COVID-19 pandemic. Besides their role as antimetabolites, these compounds serve as essential building blocks for constructing oligonucleotides (ODNs), which have applications as bio-probes and in the development of new materials. Precise modifications of heterocyclic bases and/or sugar-phosphate backbones can yield cutting-edge scaffolds that offer insights into unknown molecular mechanisms and enhance our understanding of the properties of ODNs. The aim of this Special Issue is to explore the key aspects related to the design and synthesis of novel nucleosides, nucleotides, and analogues, along with their potential applications in relevant fields. We welcome original research and reviews focusing on these topics.
Dr. Stefano D’Errico
Prof. Dr. Nicola Borbone
Dr. Andrea Patrizia Falanga
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- nucleosides, nucleotides, and nucleic acids
- modified nucleosides and nucleotides
- nucleoside and nucleotide analogues
- antimetabolites
- oligonucleotides
- organic synthesis
- bioorganic chemistry
- medicinal chemistry
