Advances in the Diagnosis and Management of Pediatric Autoimmune Diseases—2nd Edition
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".
Deadline for manuscript submissions: 30 June 2024 | Viewed by 134
Special Issue Editors
2. Clinical Academic Department of Pediatrics, National Research Center of Maternal and Child Health, University Medical Center, Nur-Sultan 010000, Kazakhstan
Interests: autoimmunity; pediatrics; rheumatology; gastroenterology; immunology
Special Issues, Collections and Topics in MDPI journals
2. Canadian Behcet and Autoinflammatory Disease Center (CAN-BE-AID), University of Western Ontario, London, ON N6A 5C1, Canada
Interests: pediatric rheumatology; autoinflammatory diseases; systemic vasculitides; systemic lupus erythematosus
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Autoimmune diseases are medical conditions driven by the persistent activation of self-reactive B and/or T lymphocytes, due to the impairment of the physiological mechanisms of central and/or peripheral immunological tolerance. In general, these are multi-factorial disorders: they recognize a background of genetic predisposition (usually polygenic, but often not well-defined), where multiple and variable environmental factors superimpose in order to trigger the autoimmune pathological process. The role of the microbiome and, in general, epigenetic factors is also gradually emerging. Autoimmune diseases can manifest in children: several clinical and pathological aspects often differ from those shown by adult patients affected by the same autoimmune disease; moreover, the longer life expectancy and the ongoing growth process in children raise specific issues and questions in terms of medical management, therapeutic approach, and long-term complications. Finally, the current COVID-19 pandemic brought additional challenges in this specific field.
In this Special Issue, we aim to cover the current knowledge, ongoing progresses, and future perspectives in biomedical research on the diagnosis and medical management of pediatric autoimmune disorders. Moreover, articles investigating and discussing the immune-pathogenic and clinical peculiarities (including comorbidities) of autoimmune diseases and immune-mediated phenomena in children are also welcome.
Dr. Dimitri Poddighe
Dr. Micol Romano
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- children
- autoimmunity
- autoinflammatory diseases
- pediatric rheumatology
- innovative and biological therapies
- comorbidity
- immune-mediated manifestations
