Microbiomes and Modulation of Therapeutic Responses in Cancer
Deadline for manuscript submissions: 15 May 2024 | Viewed by 204
Interests: cancer immunology; cancer immunotherapy; biomarkers; precision oncology; immune resistance; cancer vaccines; immune escape; immune checkpoint inhibitors
Special Issues, Collections and Topics in MDPI journals
Interests: immunomodulation; cancer vaccines; immune checkpoints and inhibitors; cancer genomics; cancer heterogeneity
One essential factor that has paramount importance for the regulation of antitumor immunity is the commensal microbiota. Precise analysis of the mechanisms underlying the microbiota-mediated immunomodulation would surely result to enhanced precision in therapeutic modalities with better clinical outcomes. In addition, the depletion of tumor-promoting or immune-suppressing bacterial strains could further enhance the clinical outcomes of immunotherapeutic strategies. Moreover, the application of immune stimulating microbial components might also favorably impact patient outcomes. Importantly, genomic profiling studies could help to identify altered microbiomes which would represent potential biomarkers for combination therapies in various types of cancers. All of the issues above will be included in our Special Issue along with the importance of microbiota in regard to cancer diagnostics and prognostics and invasive medicine.
Dr. Constantin N. Baxevanis
Dr. Angelos D. Gritzapis
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- tumor microenvironment
- cancer immunotherapy
- microbial components
- genomic profiling