Regulatory Processes of RNA in Tumorigenesis of Breast Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Tumor Microenvironment".
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 434
Special Issue Editor
Interests: macrophage colony-stimulating factor; tumor microenvironment; myeloid cells; immunotherapy; tumor-associated macrophages; innate immunity; breast cancer; cancer metastasis
Special Issue Information
Dear Colleagues,
The progression of solid tumors, including breast cancer, critically relies on phenotypic alterations in cancer cells and their supporting stroma in the tumor microenvironment (TME). These changes are driven by the activation and suppression of transcription programs that enable the formation of a pro-tumorigenic niche that facilitates the growth, neovascularization, and effective suppression of the immune response. While changes in mRNA profiles in tumor and stromal cells have been well characterized with unprecedented granularity, the changes in other RNA modalities such as RNA editing, RNA acetylation splicing, and long non-coding RNAs are largely missing.
In this Special Issue, we will focus on different RNA modalities that drive the tumorigenesis of breast cancer in human and mouse models. We will examine the effect of these processes on critical responses in the TME, including immune suppression, angiogenesis, matrix remodeling, and the invasive growth of cancer cells.
You may choose our Joint Special Issue in Current Oncology.
Dr. Nir Ben-Chetrit
Guest Editor
Manuscript Submission Information
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Keywords
- TME
- breast cancer
- innate and adaptive immunity
- ECM remodeling
- cancer-associated fibroblasts
- RNA editing
- RNA acetylation
- splicing
- long non-coding RNA
