The Genetic Analysis and Clinical Therapy in Lung Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: 10 January 2025 | Viewed by 151
Special Issue Editors
Interests: lung cancer; survival; GWAS; germline variants; immunotherapy; pharmacogenomics
Interests: cancer genetics; tumor progression; deep-next generation sequencing; liquid biopsy; circulating tumor DNA; personalized therapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
While smoking stands as the predominant risk factor for lung cancer, genetics also plays a significant role in predisposing patients to this malignancy, with germline variations potentially influencing disease progression. Over recent decades, molecular profiling has emerged as a critical tool for stratifying patients based on specific somatic mutations, enabling the utilization of multiple targeted therapies. The introduction of immunotherapy has marked a revolution in lung cancer treatment, substantially enhancing patient outcomes. However, disease progression, resistance to targeted drugs and a lack of responsiveness to immunotherapy remain major challenges in NSCLC cancer treatment, which still has low survival rates.
Our Special Issue seeks to unravel the intricate genetic aspects of this complex disease, exploring somatic mutations, biomarkers, germline variants, and the molecular mechanisms that drive lung cancer. We aim to bridge the gap between scientific discovery and clinical practice, with a particular focus on personalized medicine approaches tailored to individual patients. This Special Issue also aims to explore therapeutic innovations, from targeted therapies to immunotherapies, as well as effective strategies to monitor or predict cancer resistance, with the goal of improving patient outcomes and quality of life.
We eagerly await your upcoming scientific contributions which will be published in Cancers (ISSN 2072-6694; Impact Factor 5.2), as we work towards a future where lung cancer is better understood and more effectively treated.
In this Special Issue, original research articles and reviews are welcome.
Dr. Francesca Colombo
Dr. Frullanti Elisa
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- lung cancer
- biomarkers
- genetic variants
- innovative technologies
- targeted therapy
- immunotherapy
- personalized therapy
- survival
- liquid biopsy pharmacogenomics
