Recent Developments in Proton Therapy of Head and Neck Cancer

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".

Deadline for manuscript submissions: 10 March 2025 | Viewed by 69

Special Issue Editors

Memorial Sloan-Kettering Cancer Center, New York, NY, USA
Interests: head and neck cancers; skin cancers; thyroid cancer; mouth cancer; protons

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Guest Editor
Memorial Sloan-Kettering Cancer Center, New York, NY, USA
Interests: head and neck cancers; skin cancers; thyroid cancer; mouth cancer; protons

Special Issue Information

Dear Colleagues,

Head and neck cancer is a broad term, encompassing malignancies ranging from the paranasal sinuses, nasal cavity to the hypopharynx. Advancements in radiation technology, organ-preserving surgical techniques and the use of multimodality therapy have led to a paradigm shift in management, with the goal of toxicity reduction and possibly improved efficacy in select scenarios.

As the incidence of head and neck cancer in younger patients increases along with its high cure rates, patients are living longer, making long-term toxicity a significant concern. The implications are not limited to patient suffering from these long-term toxicities, but also the increased hospital visits increasing the economic burden.

Proton therapy is an emerging treatment modality for head and neck malignancies owing to its unique ability to spare critical organs in the head and neck using the Bragg-peak. This Special Issue aims to highlight novel advancements in proton radiation that could improve long-term toxicity and outcomes in head and neck cancer management. The goal is to have a balanced view on proton therapy on the pros and cons for each disease subsite within the head and neck, reviewing the current evidence-based literature. In addition to the benefits of proton therapy, we will also address the complications associated with this technology and on-going efforts to mitigate these toxicities.  

In this Special Issue, original research articles and reviews are welcome.  

We look forward to receiving your contributions.

Dr. Nancy Lee
Dr. Irini Youssef
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • head and neck
  • intensity-modulated proton radiation
  • particle therapy
  • toxicity
  • outcomes

Published Papers

This special issue is now open for submission.
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