Ovarian Cancer Progression: From Experimental Models to Clinical Applications (Volume II)

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Methods and Technologies Development".

Deadline for manuscript submissions: 22 November 2024 | Viewed by 102

Special Issue Editors


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Guest Editor
Department of Chemistry and Chemical Biology, Stevens Institute of Technology, Hoboken, NJ 07030, USA
Interests: ovarian cancer; mesothelial cells; live-cell imaging; metastasis; basement membrane; extracellular matrix
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Gynecology Obstetrics and Gynecologic Oncology, Poznan University of Medical Sciences, Poznań, Poland
Interests: ovarian cancer; extracellular vesicles; metastasis; cancer genomics; mathematical modeling; omics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is the second edition of the Special Issue “Ovarian Cancer Progression: From Experimental Models to Clinical Applications”, available at https://www.mdpi.com/journal/cancers/special_issues/OCPFEMTCA.

The combination of cytoreductive surgery and chemotherapy for ovarian cancer is initially successful in decreasing tumor volume; however, the management of recurrent and progressive disease remains a significant treatment challenge. Discerning the enormous complexity of disease progression, through efforts that integrate disease biology with high-throughput computation and image-guided approaches, will contribute to the development of new treatment strategies. This Special Issue will be a platform to present interdisciplinary views about ovarian cancer progression. We would like to invite leaders in the field of ovarian cancer cell biology, computational biology, clinical diagnosis, and management. Authors should discuss the latest advances in ovarian cancer models (tissue and mouse models) and computational (omics, artificial intelligence) and imaging approaches. We especially encourage translational studies that identify links between biology and clinical application. We encourage submitting both original research and review articles. The focus areas include, but are not limited to:

  • Cell biology of disease progression.
    • Spheroids, organoids, patient-derived xenografts, and genetically modified mouse models to study the biology of disease progression.
    • Biology of tumor microenvironment: The contribution of mesothelial, mesenchymal, neuronal, fibroblastic, and immune cells to tumor progression.
  • Omics and computational approaches to discover vulnerabilities of progressive disease.
    • Drug screens;
    • Genomics/proteomics;
    • Immunogenomics;
    • Radiomics;
    • Artificial-intelligence-guided experimental approaches.
  • Clinical diagnosis and management of disease progression.
    • Impact of chemotherapy on metastasis;
    • Targeted therapies in relapsed tumors;
    • Imaging of recurrent disease;
    • Surgical management of recurrent disease;
    • Intraoperative imaging;
    • Artificial intelligence-based patient stratification.

We strongly encourage studies that combine focus areas and methodologies.

Dr. Marcin Iwanicki
Dr. Mikołaj Piotr Zaborowski
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ovarian cancer progression
  • ovarian cancer spheroids
  • ovarian cancer organoids
  • ovarian cancer patient-derived xenograft models
  • genetically modified mouse models of ovarian cancer
  • mesothelial cells
  • mesenchymal stem cells
  • cancer-associated fibroblasts
  • ovarian cancer innervation
  • immune models of ovarian cancer
  • omics of ovarian cancer
  • clinical imaging of ovarian cancer
  • metastasis
  • relapse
  • modelling

Published Papers

This special issue is now open for submission.
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