Lectins in Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Metastasis".
Deadline for manuscript submissions: 25 November 2024 | Viewed by 79
Special Issue Editors
Interests: collectins; ficolins; complement activation
Special Issue Information
Dear Colleagues,
Lectins are produced by bacteria, protists, fungi, plants, invertebrates, and vertebrates. They are classified into a variety of families, depending on host, structure, and function. Their carbohydrate/glycoconjugate recognition is a ubiquitous mode of molecular interactions and signalling. Neoplastic transformation is associated with, among other things, alterations in the cell surface. Due to an abnormal glycosylation pattern, cancer cells may be recognised by endogenous defence lectins, which may contribute to their elimination. On the other hand, they possess a variety of mechanisms of escape from a host’s immunity. Furthermore, cancer cells may employ lectins to facilitate metastatic spread. The specific recognition of cancer antigens by exogenous lectins makes possible their usage in diagnostics and therapy.
This Special Issue will be focused on the multiway associations of lectins with cancer, including primarily the following:
- Lectins in anti-cancer defence.
- Lectins in cancer diagnostics and treatment.
- Involvement of lectins in the epithelial to mesenchymal transition and metastasis.
- Expression of lectins in cancer (cancer cells, the tumour microenvironment, and hosts in general).
- Interactions of lectins with cancer cells.
- Interactions of lectins with oncogenic pathogens.
- Contribution of lectins to chronic inflammation.
- Cancer sugar code.
Prof. Dr. Maciej Cedzyński
Prof. Dr. Anna S. Świerzko
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- lectin
- sugar code
- epithelial to mesenchymal transition (EMT)
- metastasis
- complement
- oncogenic pathogen
