Communication and Accessibility in the Tumor Microenvironment as a Therapeutic Target
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: 20 December 2024 | Viewed by 254
Special Issue Editors
Interests: 3D bioprinting; bioinks; hydrogels; pathological processes; cancer; cancer stem cells; tumor microenvironment; organoids; cancer diagnosis; cancer treatment; translational research; personalized medicine; tumor-on-a-chip; metastasis-on-a-chip; organ-on-a-chip
Interests: organoids; pathological processes; cancer; cancer stem cells; tumor microenvironment; cancer diagnosis; cancer treatment; translational research; personalized medicine; tumor-on-a-chip; metastasis-on-a-chip; organ-on-a-chip; 3D bioprinting; bioinks; hydrogels
Special Issue Information
Dear Colleagues,
The tumor microenvironment (TME) is a key factor that orchestrates tumor processes in different ways. The TME is constituted of cellular components comprising cancer stem cells and differentiated cancer cells, as well as stromal cells as mesenchymal stem cells, cancer-associated fibroblasts, endothelial cells, and immune system cells. There has been a tendency to simplify the TME to these aforementioned cellular components, but it also includes a complex and dynamic cellular communication network consisting of cytokines, growth factors, extracellular vesicles, miRNAs, among others, and an all-encompassing extracellular matrix (ECM). Currently, cancer therapies are advancing and are not exclusively directed at a single cell type, but rather target the entire TME complex, including cellular communication and the ECM that supports it.
This Special Issue aims to highlight the role of tumor communication and the ECM in treatment resistance, as well as being the objects of new targeted therapies. We are pleased to include original articles and reviews in this Special Issue.
Dr. Gema Jiménez-González
Dr. Carmen Griñán-Lisón
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- tumor microenvironment
- cellular communication
- tumor secretome
- signaling
- extracellular matrix
- cancer treatment
- targeted treatment
