Advances in the Molecular Biology and Pathology of Breast Cancer

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".

Deadline for manuscript submissions: 23 August 2024 | Viewed by 235

Special Issue Editor


E-Mail Website
Guest Editor
Discipline of Pathology, School of Medicine, Lambe Institute for Translational Research, University of Galway, H91 TK33 Galway, Ireland
Interests: breast cancer; biomarker; triple negative breast cancer; molecular biology; pathology

Special Issue Information

Dear Colleagues,

Breast cancer is one of the most prevalent malignancies worldwide, being the most commonly diagnosed cancer and leading cause of cancer-related deaths in women. Over the last two decades, there have been significant advances in our understanding of the molecular biology and pathology underlying breast cancer that have led to improvements in the management and outcomes of this disease. Comprehensive and multi-layered analysis has revealed the molecular and biologic heterogeneity of breast cancer with the recognition of distinct subtypes linked to different aetiological pathways. These efforts have affirmed hormone receptor and HER2 signalling pathways as major biological drivers of breast cancer. Classification systems are evolving that integrate molecular and morphologic information, and complex genomic assays now form part of the diagnostic armamentarium that informs management decisions. More recently, molecular targets have emerged as promising therapeutic options, particularly in the advanced setting. Notwithstanding the tremendous advances made, treatment options remain limited for some subtypes of breast cancer for which the prognosis remains poor. This Special Issue will cover recent advances in the molecular biology and pathology of breast cancer that work towards improving the diagnosis, management and outcomes for patients with the disease. 

Prof. Dr. Grace Callagy
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • breast cancer
  • molecular biology
  • molecular mechanisms
  • biologic heterogeneity

Published Papers

This special issue is now open for submission.
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