Cell Death in Gynecologic Cancers

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Tumor Microenvironment".

Deadline for manuscript submissions: 30 April 2024 | Viewed by 127

Special Issue Editors


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Guest Editor
Department of Obstetrics and Gynecology, Center for Reproductive Health Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA
Interests: endometrium physiology; embryo implantation; decidualization; endometrial cancer; endometrial hyperplasia; endometriosis
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Guest Editor
Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
Interests: gynencogical cancer; endometrial cancer

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Guest Editor
Department of Obstetrics and Gynecology, Center for Reproductive Health Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA
Interests: ovarian cancer; pancreatic cancer; breast cancer; DNA damage and repair; drug development; reproductive physiology

Special Issue Information

Dear Colleagues,

As is well known, cell death, particularly apoptosis, is one of the most widely studied processes among cancer biologists. Understanding apoptosis in disease conditions is very important as it not only gives an understanding of the pathogenesis of a disease but may also leave potential clues on how the disease can be treated by inducing the apoptosis. In cancer, there is a loss of balance between cell division and cell death, and cells that are destined to die do not die because of their changed behaviors (loss or gain of functions due to mutations) in the tumor-promoting microenvironment. For example, the downregulation of p53, a tumor suppressor gene, which results in reduced apoptosis and enhanced tumor growth and development, and the inactivation of p53, regardless of the mechanism, has been linked to many human cancers. However, being a double-edged sword, apoptosis can be the cause of the problem as well as the solution, as many have now ventured into the quest for new drugs targeting various aspects of apoptosis. Hence, apoptosis plays an important role in carcinogenesis as well as cancer treatment.

With this aim, this Special Issue of Cancers has been dedicated to the unique theme “Cell Death in Gynecologic Cancers”. It is my privilege to cordially invite researchers to submit original research papers and systematic reviews dedicated to this special theme.

Dr. Pooja Popli
Dr. Vishal Chandra
Dr. Vijayalaxmi G. Gupta
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • apoptosis
  • cell death
  • gynecologic cancers
  • breast cancer
  • endometrial cancer
  • endometrial hyperplasia
  • ovarian cancer

Published Papers

This special issue is now open for submission.
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