The Role of Microbiota in Modulating Inflammatory Diseases

A special issue of Biomolecules (ISSN 2218-273X).

Deadline for manuscript submissions: closed (28 February 2022) | Viewed by 260

Special Issue Editor


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Guest Editor
Institute for Neuroimmunology and Multiple Sclerosis Research, Göttingen, Germany
Interests: blood-brain barrier; immune cells; multiple sclerosis; experimental autoimmune encephalomyelitis; two-photon microscopy; B cells; T cells; dendritic cells; macrophages; astrocytes; microglia; oligodendrocytes; neurons; central nervous system; autoimmune disease; ion channels; calcium signaling
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Special Issue Information

Dear Colleagues,

Humans harbor a plethora of commensal microorganisms, which colonize the digestive tract, the respiratory tract, and the skin. They have been found to exist at a ratio of approximately 1:1 with human cells and as such, they have been recognized as playing an integral role in human development and pathophysiology. This discovery was made possible in part by the introduction of “germ-free” rats and mice in the 1940s and 1950s, which paved the way for seminal work demonstrating how perturbations in the commensal gut microbiota and enteric pathogens affect chronic inflammatory diseases, autoimmunity, and cancers. More recent studies have even demonstrated direct links between the gut microbiota and the central nervous system, which is protected from the periphery by physiological barriers. It is therefore safe to say that commensal microorganisms can have profound impacts on the body.

An increasing number of scientists are studying the intricacies of microorganisms colonizing human beings and animals used in research in an effort to shed light on specific biological mechanisms by which they influence the onset and/or course of diseases. This field of research is of vital importance as it will help shape the medical approach of the future. The aim of this Special Issue is thus to promote the dissemination of avant-garde research in the field of microbiota and encourage interactions between scientists. In order to focus on the subject of this issue, we are inviting clinician­s and researchers to submit their original research manuscripts, review articles, and short communications discussing the molecular interactions between the microbiota and the body in the context of inflammatory diseases.

Dr. Marc André Lécuyer
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • microbiota
  • inflammatory diseases
  • cancer
  • autoimmunity
  • gastrointestinal diseases
  • gut-brain axis
  • commensal microorganisms
  • immune system
  • bacteria
  • mucosal barriers

Published Papers

There is no accepted submissions to this special issue at this moment.
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