Cytoskeleton Structure and Dynamics in Health and Disease

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Biomacromolecules: Proteins".

Deadline for manuscript submissions: 20 December 2024 | Viewed by 73

Special Issue Editors

E-Mail Website
Guest Editor
Gene and Linda Voiland School of Chemical Engineering and Bioengineering, Washington State University, Pullman, WA 99163, USA
Interests: regulation of actin dynamics by actin-binding proteins; protein structure and protein-protein interactions; protein engineering; circular dichroism

E-Mail Website
Guest Editor
PhysioLab, University of Florence, 50019 Sesto Fiorentino, FI, Italy
Interests: single cell mechanics; mechanics of motor and cytoskeletal proteins; mechanics and energetics of motor proteins in vitro and in situ; force spectroscopy; optical tweezers; AFM; confocal microscope; TIRF

Special Issue Information

Dear Colleagues,

The mechanical properties of a cell are determined by the dynamics of the cytoskeleton and membrane–cytoskeleton associations. These also play a crucial role in cellular shape, morphology changes, and mechanical signal transduction in living cells. Cells are able to contract, move, invade, and undergo processes like tissue regeneration and cellular transformation due to the organization and rearrangement of the cytoskeleton. In this Special Issue of Biomolecules, we invite contributions, in the form of original research articles and reviews, related to the theme “cytoskeleton structure and dynamics in health and disease”. 

Articles that focus on functional and structural aspects from cellular or molecular perspectives are particularly welcome. The topics of interest include, but are not limited to, the following:

  • Structural and functional aspects of cytoskeletal components.
  • Cytoskeleton during the development of specialized cellular domains (e.g., axons).
  • Cytoskeleton in cell division and cell migration.
  • Cytoskeletal changes in cellular transformation and cancer.
  • Cytoskeleton in muscle cells.
  • Cytoskeleton and mechano-transduction.

Dr. Alla S. S. Kostyukova
Dr. Pasquale Bianco
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • actin
  • myosin
  • cytoskeleton
  • membrane-cytoskeleton associations
  • mechanotransduction
  • cytokinesis
  • nuclear cytoskeleton
  • contractile systems
  • cell motility
  • cell morphogenesis
  • cell adhesions
  • signal transduction
  • cytoskeleton structure and dynamics
  • microtubules, actin filaments
  • intermediate filaments organization

Published Papers

This special issue is now open for submission.
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