Exploring the Dynamics of Protein Lysine Methylation and Its Implication in Disease
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Biomacromolecules: Proteins".
Deadline for manuscript submissions: 1 June 2024 | Viewed by 94
Special Issue Editor
Interests: the discovery and characterization of how proteins coordinate and work; functional proteomics; how proteins dynamically interact with each other; how PTM-modifying enzymes select substrates; changes in protein signaling or regulatory networks that accompany disease progression or resistance to treatment
Special Issue Information
Dear Colleagues,
This Special Issue delves into the dynamic world of protein lysine methylation within the realm of functional proteomics, aiming to illuminate its crucial roles in both normal biology and disease progression. Lysine methylation, a pivotal post-translational modification, orchestrates a multitude of cellular functions by regulating protein–protein interactions, enzymatic activities, and signaling pathways. This compilation of articles endeavors to unravel the complexities of lysine methylation, exploring its impact on protein dynamics, enzymatic substrate selection, and alterations in regulatory networks associated with various diseases.
From the nuanced understanding of lysine methylation's role in protein coordination to its implications in disease pathogenesis and therapy resistance, this issue showcases cutting-edge research from international researchers. The insights gained from these studies promise to advance our understanding of basic biology regulated by protein lysine methylation and its impact on disease mechanisms, paving the way for innovative interventions targeting protein lysine methylation in diverse pathological conditions.
Dr. Kyle K. Biggar
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- protein regulation
- disease mechanisms
- biomarkers and therapeutic targets
- cellular signaling
- mass spectrometry
