Neurocognitive Disorders: From Molecular Mechanisms to Therapeutic Strategies

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".

Deadline for manuscript submissions: 31 July 2024 | Viewed by 93

Special Issue Editor


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Guest Editor
Department of Psychiatry & Behavioral Sciences, Dell Medical School, The University of Texas at Austin, Austin, TX, USA
Interests: affective functions; brain functions; genetic mechanisms controlling brain structure and functions; mood disorder phenotypes; human studies

Special Issue Information

Dear Colleagues,

Neurocognitive disorders affecting cognitive domains such as attention, memory, language, social cognition, and executive functions are highly prevalent and account for a significant global burden of diseases. Although the different cognitive domains are well mapped in terms of the mammalian brain anatomical regions supporting cognition and brain regional connective network functions necessary for engendering various cognitive functions, the molecular mechanisms underlying normal cognitive functions, which, when impaired, can lead to a plethora of cognitive deficits and disorders of cognition, are understudied. Various neurocognitive disorders across the lifespan have been associated with molecular abnormalities in different brain and peripheral systems. However, what roles specific molecular mechanisms, including dosage-sensitive measures, play in the development of neurocognitive disorders is not well understood.

In this Special Issue devoted to neurocognitive disorders, we expect contributions from leading scientists, physicians, and other experts on molecular studies of model systems in the domains of neurocognition in health and diseases. We are particularly interested in manuscripts that contribute to a better understanding of the molecular repertoires (from genes/DNA level to transcripts/RNA level to protein-level measures) of various cognitive functions and dysfunctions across the developmental lifespan in rodent and cellular models. By accumulating a collection of molecular studies of neurocognitive disorders using preclinical approaches, we will attempt to bridge the knowledge gap between the brain's anatomical and functional basis of cognition and the molecular mechanisms underlying cognitive functions in health and diseases. The contributions from this special issue will inform clinical studies and future therapeutic avenues.

Dr. Mbemba Jabbi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neurocognition
  • molecular mechanisms
  • brain anatomy
  • disease

Published Papers

This special issue is now open for submission.
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