Cannabinoid Receptors in the Central Nervous System
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Natural and Bio-inspired Molecules".
Deadline for manuscript submissions: 31 May 2024 | Viewed by 155
Special Issue Editor
Special Issue Information
Dear Colleagues,
The chemical constituents of cannabis (Cannabis sativa) are collectively referred to as cannabinoids, many of which exhibit potent systemic effects. Cannabinoid receptors 1 and 2 are known as CB1 and CB2, and endogenous ligands for these receptors such as 2-AG (2-Arachidonoyl Glycerol) have been discovered. Since the endocannabinoid system was discovered to be a retrograde synaptic transmitter by three independent laboratories (Profs. Nicoll, Kano, and Regehr) almost simultaneously about 20 years ago, significant progress has been made in this field, including the finding that CB1/CB2 receptors are critical for cognitive functions such as extinction learning and memory acquisition. However, it is still unclear which endocannabinoids play critical roles in the various neural functions. Recently, a new cannabinoid receptor, GPR55, was identified. GPR55, similar to CB1/CB2, is a G-protein-coupled receptor (GPCR) for cannabinoids, though much of its physiological function still remains unknown. Thus, the purpose of this Special Issue is to present ambitious studies that attempt to elucidate the functions of various cannabinoid receptors and their physiological agonists, from new methods and perspectives. We also welcome submissions on preclinical and basic research on cannabinoid receptors as targets for the development of central nervous system drugs, which have attracted much attention in recent years.
Prof. Dr. Yasushi Kishimoto
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- learning and memory
- endocannabinoid system
- cognitive flexibility
- cerebellum
- hippocampus
