The Role of Scaffold Proteins in Human Diseases

A special issue of Biomolecules (ISSN 2218-273X).

Deadline for manuscript submissions: 15 August 2024 | Viewed by 96

Special Issue Editors


E-Mail Website
Guest Editor
Institute of Molecular Life Sciences, HUN-REN Research Centre of Natural Sciences, Budapest, Hungary
Interests: cell signalling; tyrosine kinases; scaffold proteins; SH2 and SH3 domains; Ras signalling
Institute of Molecular Life Sciences, HUN-REN Research Centre of Natural Sciences, Budapest, Hungary
Interests: cell communication; signal transduction; disease models; cancer cell biology; cancer evolution; EGFR signalling; metastasis formation

Special Issue Information

Dear Colleagues,

Scaffold proteins play a crucial role in the organization and regulation of cellular signalling pathways. They act as molecular platforms that bring together various signalling molecules, facilitating their interaction and coordination. The significance of scaffold proteins in human diseases is vast, as they can influence the development, progression, and treatment of various conditions. Understanding the role of scaffold proteins in different cellular processes is essential for unravelling the molecular mechanisms underlying human diseases, such as cancer progression, neurological disorders, immune system regulation, cardiovascular diseases, and metabolic disorders. Targeting scaffold proteins or their associated signalling pathways may offer new therapeutic strategies for the treatment of various disorders. However, it is important to note that proteomic/epigenomic/genomic research in this field is ongoing, and our understanding of scaffold proteins and their implications in human diseases continues to evolve.

In this Special Issue of Biomolecules, we will provide an open access platform for reviews and original research papers describing all aspects of research on scaffold proteins in human diseases.

Prof. Dr. László Buday
Dr. Virag Vas
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • scaffold proteins
  • cellular signalling
  • protein–protein interactions
  • protein domains
  • human diseases
  • drug targets
  • protein complex formation
  • pathogenic alterations

Published Papers

This special issue is now open for submission.
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