Targeting Sodium Channels and Pumps for Cancer Therapy
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: 31 May 2024 | Viewed by 202
Special Issue Editor
Special Issue Information
Dear Colleagues,
With more than two decades of research history, it is evident that voltage-gated sodium channels (VGSCs) and the associated sodium-potassium ATPase pumps are involved in the growth, motility, invasiveness and metastasis of aggressive carcinomas. Thus, they are implicated as excellent biomarkers and targets for treatment of about two-thirds of cancers. Genetic and epigenetic changes have been implicated in the VGSC overexpression. Both the blockade of sodium pumps and activation of the SRC pathway have been implicated in the anti-cancer effects of glycoside drugs.
This Special Issue of Biomolecules is dedicated to publishing the most recent thoughts and developments in cancer treatments that target the sodium handling system. Therefore, we encourage submissions of original research or review articles on novel treatments or results that may contribute to the development of cancer treatments.
Prof. Dr. Dennis Paul
Guest Editor
Manuscript Submission Information
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Keywords
- carcinomas
- voltage-gated sodium channels
- Na+, K+-ATPase
