New Insights into Functional and Regulatory Aspects of Gene Expression in Protozoan Parasites

A special issue of Applied Microbiology (ISSN 2673-8007).

Deadline for manuscript submissions: 31 December 2024 | Viewed by 66

Special Issue Editors

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Guest Editor
College of Veterinary Medicine, China Agricultural University, Beijing 100193, China
Interests: Eimeria spp.; Toxoplasma gondii; regulation of endogenous development; anticoccidial drug resistance; anticoccidial vaccines

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Guest Editor
Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA 90024, USA
Interests: molecular biology; parasitology; protozoa; pathogens; trichomonas vaginalis; schistosoma; sexually transmitted disease; bioinformatics; genetics

Special Issue Information

Dear Colleagues,

Protozoan parasites are a diverse group of unicellular, eukaryotic microorganisms that cause a wide range of diseases in humans and animals. Unlike bacteria and viruses, protozoa have developed a more sophisticated functional gene repertoire and regulatory mechanisms during evolution. These features allow them to establish infection, evade the host immune system, and ensure their survival and proliferation. Recent advancements in molecular biology, genomics, and computational approaches have shed light on the complex mechanisms governing gene expression in protozoan parasites. This Special Issue, entitled “New Insights into Functional and Regulatory Aspects of Gene Expression in Protozoan Parasites”, aims to provide a platform to showcase recent, fundamental research progress on unicellular parasites at the molecular level. Its focal points, among others, are as follows:

- The deployment of genetic tools for the manipulation of genetically intractable protozoan parasites.

- The functional characterization of protein-coding genes that are implicated in pathogenesis, life cycles, modes of transmission, host–parasite interactions, and other key processes of parasitic protozoa.

- The regulation of gene expression at multiple levels in cells of protozoa parasites, which include, but are not limited to, epigenetic modifications, small non-coding RNAs, transcriptional and translational regulation, spatial and temporal control of protein synthesis, etc.

- Comparative studies that reveal parasite diversity, evolution, their genetic basis of pathogenicity and drug resistance, and adaptations to different hosts and environments.

- The integration of cutting-edge computational approaches such as artificial intelligence and machine learning in analyzing large-scale multiomics data of protozoan parasites.

- The identification and validation of key antigens that facilitate drug discovery and vaccine development against infections from protozoan pathogens.

Dr. Xian-Yong Liu
Dr. Shuqi Wang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Microbiology is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • protozoan parasites 
  • parasite diversity
  • protozoan pathogens
  • drug discovery and vaccine

Published Papers

This special issue is now open for submission.
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