Next Article in Journal
Effect of Pulsed Electric Fields on the Recovery of Antioxidant Protein Extracts from Fish Side Streams
Previous Article in Journal
Demographic Associations of Stress-Induced Hair Loss Assessed in Medical Students
 
 
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Proceeding Paper

Ayurvedic Milk Powder as a Health Drink—An Innovative Approach in Antenatal Health Care—A Research Proposal †

by
Anuja Ajithakumari Rajendrakurup
*,
Vineeth Paramadam Krishnan Nair
,
Arun Mohanan
and
Ramesh Narve Venkatesha
*
Department of Rasashastra and Bhaishajya Kalpana (Medicinal Chemistry and Pharmacy), Amrita School of Ayurveda, Amrita Vishwa Vidyapeetham, Vallikavu, Clappana (PO), Kollam 690525, India
*
Authors to whom correspondence should be addressed.
Presented at the 2nd International Electronic Conference on Foods—“Future Foods and Food Technologies for a Sustainable World”, 15–30 October 2021; Available online: https://foods2021.sciforum.net/.
Biol. Life Sci. Forum 2021, 6(1), 16; https://doi.org/10.3390/Foods2021-10972
Published: 14 October 2021

Abstract

:
Ayurvedic preceptors place much emphasis on nutrition, especially during antenatal and postnatal periods, which may reduce the likelihood of medical complications both during and after pregnancy. Classic Ayurvedic texts mention medicated milk as an important part of prenatal care for pregnant women. By evaluating the effects of the herbal drugs contained in these formulations, one can understand the pharmacodynamics of these products. The medicated milk, when converted into milk powder, represents a healthier alternative to malted milk powder.

1. Introduction

A healthy diet plays a significant role in pregnancy and lactation. An adequate and balanced diet can help to prevent prenatal complications and aid in the proper development of the fetus. The food taken by the mother is responsible for providing both the fetus and the mother with nutrition. In Ayurveda, antenatal as well as postnatal care are of paramount importance. Ayurveda emphasizes certain month-wise diet patterns and daily regimens for pregnant women, which are known as Māsānumāsika paricarya. Many Ayurvedic scholars provide detailed explanations regarding the month-by-month diet and regimen. These unique diet patterns reduce the risk of miscarriage early in pregnancy, improve fetal nutrition during the second trimester, and improve maternal health during the third trimester [1]. Sahasrayogam, a book about Ayurvedic treatments, mentions a particular drug used to prepare medicated milk every month [2]. Starting from the first month, medicated milk should be prepared with Sida cordifolia, Ipomea sepiaria, Solanum indicum, Desmodium gangeticum, Tinospora cordifolia, Solanum xanthocarpum, Hordeum vulgare, Chonemorpha macrophylla, Asparagus racemosus in the subsequent months.

2. Methodology

This study performs a review of the literature using authentic Ayurvedic textbooks and scientific articles in PubMed and Google Scholar. Databases were searched with the keywords Sida cordifolia, Ipomea sepiaria, Solanum indicum, Desmodium gangeticum, Tinospora cordifolia, Solanum xanthocarpum, Hordeum vulgare, Chonemorpha macrophylla, Asparagus racemosus separately, as well as these drugs AND Ayurveda, plus Ayurveda AND antenatal care. We selected articles based on both their title and content for relevance. While several review articles discussed the use of Ayurvedic milk during pregnancy, no clinical trials have looked directly at this issue. The effect of specific drugs on pregnancy has been studied in many preclinical and clinical trials.

3. Medicated Milk

Medicated milk, or Kṣīrapākā, is a unique Ayurvedic formulation in which milk is the basic component. Astringent or pungent drugs usually benefit from this method. It masks the bitter taste of drugs and reduces the intensity of pungent drugs. The therapy enhances the patient’s strength and endurance when they are fatigued from illness or other treatments. The preparation method of this medicine is more suitable for conditions requiring the use of fat-soluble ingredients [3]. Milk is often described as the best rejuvenator and is a commonly used drink from birth to death. Milk adds nutritional value along with the therapeutical effects of added drugs.
Drugs, milk, and water are boiled together at a specific ratio to prepare medicated milk. These are boiled in a mild fire until only the milk part remains. Different Ayurvedic preceptors have given different ratios of drugs, milk and, water for the preparation of the formulation. According to Śārangadhara samhita, the proportion of drugs, milk, and water is 1:8:32, and according to Yadavji Trikamji, the author of Dravyaguṇa, the ratio is 1:15:15. While explaining about laśuna Kṣīrapākā (medicated milk prepared with garlic), the author of Bhaiṣajya ratnāvali mentions the ratio as being 1:8:8 [4] (Table 1).

4. Month Wise Drugs for Medicated Milk

The drug mentioned in the first month of pregnancy is Sida cordifolia, which belongs to the Malvaceae family. As per Ayurveda, the drug has a sweet taste, low potency, and is classified as part of the madhura skandha (group of drugs with a sweet taste) and garbhasthāpana gaṇa (antiabortifacient drug). Pregnant women may experience tender swollen breasts, nausea with or without vomiting, and increased urination during the first month of pregnancy. The flavonoids found in Sida cordifolia support the anti-oxidant activity of this plant [5]. This antioxidant property prevents conditions such as spontaneous abortion, pre-eclampsia, fetal growth restriction, etc. [6]. A number of alkaloids present in Sida cordifolia have anti-inflammatory and analgesic properties [7]. It prevents backache and leg cramps. Pregnant women can also benefit from taking the herb to relieve frequent urination and high blood pressure during the first month of pregnancy.
The drug of choice for the second month of pregnancy is Ipomea sepiaria, a member of the Convolvulaceae family. Ayurvedic preceptors list the drug under garbhasthapāna gaṇa, and mentioned it as the most appropriate drug for the procedure of pumsavana (one of the 16 rituals in the ancient Indian concept). The antioxidant, analgesic and anti-inflammatory properties of Ipomea sepiaria make it useful in a variety of gynecological conditions.
During the fourth month of pregnancy, the most recommended drug is Desmodium gangeticum, belonging to the family Fabaceae. This herb possesses properties such as a bitter astringent taste, high potency, and is difficult to digest. It is indicated in a variety of conditions such as fever, vomiting, respiratory conditions, etc. The pterocarpanoids and gangetin it contains possess anti-inflammatory and analgesic properties [8]. The flavonoids and isoflavanoids glycosides in the drug provide the drug with significant antioxidant activity [9]. The nervous system of the fetus begins to develop during the fourth month, and the drug Desmodium gangeticum is found to have immense action in the central nervous system. The chemical components of Desmodium gangeticum can reduce constipation and emesis gravidarum symptoms.
In the third month of pregnancy, Solanum indicum, and in sixth month, Solanum xanthocarpum, both belonging to the Solanaceae family, are the preferred drugs. The most important chemicals in these herbs are saponins, glycosides, sesquiterpenoids, coumarins, etc. Solanum species are reputed for being potent antioxidants. They also prevent pregnancy-related hypertension and pedal edema.
During the fifth month of pregnancy, Tinospora cordifolia, belonging to the Menispermacea family, is the drug of choice. This drug is included under garbhasthāpana gaṇa. It is a drug rich in alkaloids, glycosides, steroids, polysaccharides, etc. It possesses a bitter astringent taste, low potency, is unctuous and is easy to digest. There are a wide range of conditions for which it is indicated, including diabetes, cardiovascular conditions, skin disorders, and rheumatic diseases. The effects of Tinospora cordifolia on oxidative stress in prenatal conditions have been studied extensively [10]. Its antidiabetic effect is contributed mainly by the tannins, alkaloids, flavonoids and saponins present in it. It also modulates the immunity of pregnant woman.
Pregnant women should consume milk prepared with Hordeum vulgare, a plant belonging to the Poaceae family, during the seventh month of pregnancy. It possesses a sweet astringent and bitter taste, and high potency. It is a good source of micronutrients as well as macronutrients. Ayurvedic preceptors mentioned it as a drug of choice in diabetes. Different pharmacological actions are possessed by it, such as antihypercholesterolemic activity, diuretic activity, fatty acid synthase inhibition, laxative effects, and lipid metabolism. A study of a fetus affected by maternal diabetes found that Hordeum vulgare actively stimulated the development of the fetal adrenal cortex [11]. In addition to promoting intestinal mobility, Hordeum vulgare is also effective in fostering lung growth in fetuses [12].
In the eighth month of pregnancy, most women use the drug Chonemorpha macrophylla, which belongs to the Apocynacea family. It possesses a bitter astringent sweet taste, high potency and is hard to digest. Chonemorpha macrophylla possessed skeletal muscle-relaxant action in an experimental model [13].
Asperagus racemosus, belonging to the Asperageacea family, is the drug of choice during the ninth month of pregnancy. It possesses a sweet bitter taste and low potency. Researchers have confirmed the galactogogue properties of Asperagus racemosus [14]. Furthermore, it increases vaginal dilation, which greatly facilitates vaginal delivery [15]. The list of drugs mentioned for preparing the medicated milk is mentioned below. (Table 2).

5. Medicated Milk Powder

Medicated milk is a type of decoction (kwātha kalpana), the shelf life of which is one day. Procuring small quantities of raw drugs from the market and preparing the medicated milk each time is a tedious process. It is possible to prepare medicated milk powder without experiencing this problem using a spray dryer. A spray dryer rapidly dries a liquid from a slurry or liquid by adding hot air to the liquid or slurry [16]. Medicated milk powder preparation requires care. The quality of the prepared powder must be assessed before packing.

6. Conclusions

Ayurvedic milk powder serves as a healthier alternative to commercial malted milk powder, as it ensures the well-being of the mother and baby. Ayurvedic milk powder may help to reduce the risks and complications associated with pregnancy when associated with normal antenatal care. This new dosage form should undergo extensive preclinical and clinical trials before being introduced to the market.

Author Contributions

A.A.R. is the main author. Throughout the work, R.N.V., A.M. and V.P.K.N. guided and made appropriate suggestions. All authors have read and agreed to the published version of the manuscript.

Funding

This research received no external funding.

Institutional Review Board Statement

Not applicable.

Informed Consent Statement

Not applicable.

Data Availability Statement

Not applicable.

Acknowledgments

All individuals consented to the acknowledgement.

Conflicts of Interest

The author declares no conflict of interest.

References

  1. Kulkarni, R.; Srilakshmi, C.; Sarada, M. Ayurveda principles of Garbhiniparicharya (prenatal care) and its scientific relevance. J. Indian Syst. Med. 2020, 8, 5. [Google Scholar] [CrossRef]
  2. Krishnanvaidyan, A.K.V.; Gopalapillai, A.S. Sahasrayogam, 35th ed.; Vidyarambham Publications: Alappuzha, India, 2017; p. 104. ISBN 81-85315-10-8. [Google Scholar]
  3. Remadevi, R. Bhaishajya Kalpana, 2nd ed.; Perfect Publications: Kottakal, India, 2006; Volume 1, p. 182. [Google Scholar]
  4. Angadi, R. A Textbook of Bhaishajya Kalpana [Pharmaceutical Science], 2nd ed.; Chaukhamba Surbharati Prakashan: Uttar Pradesh, India, 2016; pp. 104–105. ISBN 978-93-908046-3-9. [Google Scholar]
  5. Dhalwal, K.; Deshpande, Y.; Purohit, A.; Kadam, S. Evaluation of the Antioxidant Activity of Sida cordifolia. Pharm. Biol. 2005, 43, 754–761. [Google Scholar] [CrossRef] [Green Version]
  6. Jenkins, C.; Wilson, R.; Roberts, J.; Miller, H.; McKillop, J.H.; Walker, J. Antioxidants: Their Role in Pregnancy and Miscarriage. Antioxid. Redox Signal. 2000, 2, 623–628. [Google Scholar] [CrossRef] [PubMed]
  7. Sutradhar, R.K.; Rahman, A.M.; Ahmad, M.; Bachar, S.C.; Saha, A.; Roy, T.G. Anti-inflammatory and analgesic alkaloid from Sida cordifolia linn. Pak. J. Pharm. Sci. 2007, 20, 185–188. [Google Scholar] [PubMed]
  8. Ghosh, D.; Anandakumar, A. Anti-inflammatory and analgesic activities of gangetin—A pterocarpenoid from Desmodium gangeticum. Indian J. Pharmacol. 1983, 15, 391. [Google Scholar]
  9. Govindarajan, R.; Rastogi, S.; Vijayakumar, M.; Shirwaikar, A.; Rawat, A.K.S.; Mehrotra, S.; Pushpangadan, P. Studies on the Antioxidant Activities of Desmodium gangeticum. Biol. Pharm. Bull. 2003, 26, 1424–1427. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  10. Shivananjappa, M. Muralidhara Abrogation of maternal and fetal oxidative stress in the streptozotocin-induced diabetic rat by dietary supplements of Tinospora cordifolia. Nutrients 2012, 28, 581–587. [Google Scholar] [CrossRef]
  11. Hajarzadeh, A.; Jahromi, H.K.; Mokbber, H.; Jahromi, N.S.; Ghaedi, S.; Sadoughi, M. Studying histopathological effects of barley grain (Hordeum vulgare L.) on the evolution of the cortical portion of the adrenal glands in foetuses of diabetic albino rats. Comp. Haematol. Int. 2014, 24, 893–897. [Google Scholar] [CrossRef]
  12. Arbabi, F.; Minae Zangi, B.; Sadooghi, M. The effect of Hordeum vulgare L. On the Development of Lung Tissues in the Embryo of Diabetic Albino Rats. J. Comp. Pathobiol. Iran 2015, 11, 1429–1435. [Google Scholar]
  13. Roy, R.; Ray, N.; Das, A. Skeletal muscle relaxant effect of Chonemorpha macrophylla in experimental animals. Indian J. Pharmacol. 2005, 37, 116. [Google Scholar] [CrossRef]
  14. Gupta, M.; Shaw, B. A Double-Blind Randomized Clinical Trial for Evaluation of Galactogogue Activity of Asparagus racemosus Willd. Iran. J. Pharm. Res. 2011, 10, 167–172. [Google Scholar] [PubMed]
  15. Pandey, S.K.; Sahay, A.; Pandey, R.S.; Tripathi, Y.B. Effect of Asparagus racemosus rhizome (Shatavari) on mammary gland and genital organs of pregnant rat. Phytother. Res. 2005, 19, 721–724. [Google Scholar] [CrossRef] [PubMed]
  16. Wikipedia Contributors. Spray Drying. In Wikipedia, The Free Encyclopedia. 8 September 2021. Available online: https://en.wikipedia.org/w/index.php?title=Spray_drying&oldid=1043131296 (accessed on 14 September 2021).
Table 1. Ratio of ingredients.
Table 1. Ratio of ingredients.
SL. NOClassical ReferenceRatio of Drugs:Milk:Water
1Śārangadhara samhita1:8:32
2Dravyaguṇa1:15:15
3Bhaiṣajya ratnāvali1:8:8
Table 2. Month wise drugs for medicated milk.
Table 2. Month wise drugs for medicated milk.
SL. NOMonthDrugBotanical Name
1First monthBalāSida cordifolia
2Second monthLakṣmaṇaIpomea sepiaria
3Third monthBruhatīSolanum indicum
4Fourth monthAmśumatīDesmodium gangeticum
5Fifth monthGuducīTinospora cordifolia
6Sixth monthNidigdhikāSolanum xanthocarpum
7Seventh monthYavaHordeum vulgare
8Eighth monthMoraṭaChonemorpha macrophylla
9Ninth monthŚatāvarīAsperagus racemosus
Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Share and Cite

MDPI and ACS Style

Rajendrakurup, A.A.; Nair, V.P.K.; Mohanan, A.; Venkatesha, R.N. Ayurvedic Milk Powder as a Health Drink—An Innovative Approach in Antenatal Health Care—A Research Proposal. Biol. Life Sci. Forum 2021, 6, 16. https://doi.org/10.3390/Foods2021-10972

AMA Style

Rajendrakurup AA, Nair VPK, Mohanan A, Venkatesha RN. Ayurvedic Milk Powder as a Health Drink—An Innovative Approach in Antenatal Health Care—A Research Proposal. Biology and Life Sciences Forum. 2021; 6(1):16. https://doi.org/10.3390/Foods2021-10972

Chicago/Turabian Style

Rajendrakurup, Anuja Ajithakumari, Vineeth Paramadam Krishnan Nair, Arun Mohanan, and Ramesh Narve Venkatesha. 2021. "Ayurvedic Milk Powder as a Health Drink—An Innovative Approach in Antenatal Health Care—A Research Proposal" Biology and Life Sciences Forum 6, no. 1: 16. https://doi.org/10.3390/Foods2021-10972

Article Metrics

Back to TopTop