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Case Report

Early Experience of Nintedanib in COVID-19 ARDS-Related Pulmonary Fibrosis: A Case Series

by
Marwah Vikas
1,2,
Robin Choudhary
1,2,*,
Virender Malik
1,2,
Arpita Pemmaraju
1,2 and
Deepu Peter
1,2
1
Army Institute of Cardiothoracic Science, Armed Forces Medical College, 411040 Pune, India
2
Army Institute of Cardiothoracic Sciences, Department of Pulmonary, Critical Care and Sleep Medicine, 411040 Pune, India
*
Author to whom correspondence should be addressed.
Adv. Respir. Med. 2021, 89(6), 589-596; https://doi.org/10.5603/ARM.a2021.0113
Submission received: 30 March 2021 / Revised: 14 August 2021 / Accepted: 14 August 2021 / Published: 29 December 2021

Abstract

The current COVID-19 pandemic has spread like wildfire worldwide and has affected millions of people. The novel corona virus mainly affects the lungs leading to life threatening disease like acute respiratory distress syndrome (ARDS). The aftermath of the disease in form of pulmonary fibrosis is upcoming cause of further increase in morbidity and mortality. Nintedanib is an oral antifibrotics with proven role in idiopathic pulmonary fibrosis, however its use in COVID-19 related pulmonary fibrosis has not been studied. We report our early experience of use of nintedanib in COVID-19 related pulmonary fibrosis.
Keywords: SARS-CoV-2; ARDS; pulmonary fibrosis; antifibrotics; nintedanib SARS-CoV-2; ARDS; pulmonary fibrosis; antifibrotics; nintedanib

Share and Cite

MDPI and ACS Style

Vikas, M.; Choudhary, R.; Malik, V.; Pemmaraju, A.; Peter, D. Early Experience of Nintedanib in COVID-19 ARDS-Related Pulmonary Fibrosis: A Case Series. Adv. Respir. Med. 2021, 89, 589-596. https://doi.org/10.5603/ARM.a2021.0113

AMA Style

Vikas M, Choudhary R, Malik V, Pemmaraju A, Peter D. Early Experience of Nintedanib in COVID-19 ARDS-Related Pulmonary Fibrosis: A Case Series. Advances in Respiratory Medicine. 2021; 89(6):589-596. https://doi.org/10.5603/ARM.a2021.0113

Chicago/Turabian Style

Vikas, Marwah, Robin Choudhary, Virender Malik, Arpita Pemmaraju, and Deepu Peter. 2021. "Early Experience of Nintedanib in COVID-19 ARDS-Related Pulmonary Fibrosis: A Case Series" Advances in Respiratory Medicine 89, no. 6: 589-596. https://doi.org/10.5603/ARM.a2021.0113

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