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Volume 89
Issue 4
10.5603/ARM.a2021.0067
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Advances in Respiratory Medicine is published by MDPI from Volume 90 Issue 4 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Via Medica.
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Case Report

Probe-Based Confocal Laser Endomicroscopy in COVID-19

by
Igor Vladimirovich Vasilev
1,
Igor Sergeevich Mamenko
1,*,
Anna Valerievna Makarova
1,
Olga Pavlovna Sokolova
1,
Vladimir Fedorovich Lee
1,
Mahmud Mustafa Mortada
1,
Tatiana Alexandrovna Novickaya
1,2 and
Piotr Kazimirovich Yablonskii
1,2
1
Saint-Petersburg State Research Institute of Phthisiopulmonology, Saint-Petersburg, Russia
2
Saint-Petersburg State University, Medical Faculty, Saint-Petersburg, Russia
*
Author to whom correspondence should be addressed.
Adv. Respir. Med. 2021, 89(4), 456-459; https://doi.org/10.5603/ARM.a2021.0067
Submission received: 16 November 2020 / Revised: 21 March 2021 / Accepted: 21 March 2021 / Published: 15 July 2021

Abstract

Probe-based confocal laser endomicroscopy (pCLE) is a method that produces microscopic imaging of a lung tissue during bronchoscopy. We report a case ot a patient with negative nasopharyngeal swabs and suspected lung cancer who underwent pCLE. The diagnosis of COVID-19 was confirmed by PCR analyses of lavage fluid and transbrohial biopsy. The pCLE image shows density of alveolar thickened fibres, disorganization of elastin network, and multiple large drops of intraalveolar secretions. As far as we know, this is the first pCLE image discribed in patient with COVID-19 at that moment.
Keywords: confocal laser endomicroscopy; optical biopsy; COVID-19; SARS-CoV-2 confocal laser endomicroscopy; optical biopsy; COVID-19; SARS-CoV-2

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MDPI and ACS Style

Vasilev, I.V.; Mamenko, I.S.; Makarova, A.V.; Sokolova, O.P.; Lee, V.F.; Mortada, M.M.; Novickaya, T.A.; Yablonskii, P.K. Probe-Based Confocal Laser Endomicroscopy in COVID-19. Adv. Respir. Med. 2021, 89, 456-459. https://doi.org/10.5603/ARM.a2021.0067

AMA Style

Vasilev IV, Mamenko IS, Makarova AV, Sokolova OP, Lee VF, Mortada MM, Novickaya TA, Yablonskii PK. Probe-Based Confocal Laser Endomicroscopy in COVID-19. Advances in Respiratory Medicine. 2021; 89(4):456-459. https://doi.org/10.5603/ARM.a2021.0067

Chicago/Turabian Style

Vasilev, Igor Vladimirovich, Igor Sergeevich Mamenko, Anna Valerievna Makarova, Olga Pavlovna Sokolova, Vladimir Fedorovich Lee, Mahmud Mustafa Mortada, Tatiana Alexandrovna Novickaya, and Piotr Kazimirovich Yablonskii. 2021. "Probe-Based Confocal Laser Endomicroscopy in COVID-19" Advances in Respiratory Medicine 89, no. 4: 456-459. https://doi.org/10.5603/ARM.a2021.0067

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