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Review

Tiotropium and Its Efficacy in the Treatment of COPD

by
Maciej Kupczyk
1,*,
Paweł Szepiel
2 and
Piotr Kuna
1
1
Division of Internal Medicine, Asthma and Allergy, Medical University of Lodz, 90-153 Łódź, Poland
2
Boehringer Ingelheim, Warsaw, Poland
*
Author to whom correspondence should be addressed.
Adv. Respir. Med. 2015, 83(3), 229-237; https://doi.org/10.5603/PiAP.2015.0037
Submission received: 25 March 2015 / Revised: 30 April 2015 / Accepted: 30 April 2015 / Published: 30 April 2015

Abstract

Exacerbations of chronic obstructive pulmonary disease (COPD) have a negative effect on the clinical course and outcome of the disease thus causing considerable social and economic burden. As the natural course of the disease may vary, the treatment should take into account an individual approach to a patient. The appropriate treatment makes it possible to control the symptoms, improves effort tolerance and decreases the risk of exacerbations and death. Tiotropium is a muscarinic receptor antagonist, which is taken once daily, in maintenance therapy, in every stage of the disease progress. The efficacy of tiotropium in regards to exacerbations of chronic obstructive pulmonary disease has been evaluated in many clinical trials against placebo and several different active comparators. This review presents the results of those studies with the main goal to evaluate the efficacy of treatment with tiotropium in terms of prevention and course of exacerbations.
Keywords: tiotropium; COPD; exacerbations tiotropium; COPD; exacerbations

Share and Cite

MDPI and ACS Style

Kupczyk, M.; Szepiel, P.; Kuna, P. Tiotropium and Its Efficacy in the Treatment of COPD. Adv. Respir. Med. 2015, 83, 229-237. https://doi.org/10.5603/PiAP.2015.0037

AMA Style

Kupczyk M, Szepiel P, Kuna P. Tiotropium and Its Efficacy in the Treatment of COPD. Advances in Respiratory Medicine. 2015; 83(3):229-237. https://doi.org/10.5603/PiAP.2015.0037

Chicago/Turabian Style

Kupczyk, Maciej, Paweł Szepiel, and Piotr Kuna. 2015. "Tiotropium and Its Efficacy in the Treatment of COPD" Advances in Respiratory Medicine 83, no. 3: 229-237. https://doi.org/10.5603/PiAP.2015.0037

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