Pulmonary Pathology in Patients with Ulcerative Colitis Treated with Mesalazine—A Challenging and Complex Diagnostic Problem. Case Series and Literature Review

Kacprzak, Aneta; Siemion-Szcześniak, Izabela; Szturmowicz, Monika; Bestry, Iwona; Langfort, Renata; Kuś, Jan

doi:10.5603/PiAP.2014.0047

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Pulmonary Pathology in Patients with Ulcerative Colitis Treated with Mesalazine—A Challenging and Complex Diagnostic Problem. Case Series and Literature Review

by

Aneta Kacprzak

^1,*,

Izabela Siemion-Szcześniak

¹,

Monika Szturmowicz

¹,

Iwona Bestry

²,

Renata Langfort

³ and

Jan Kuś

¹

I Department of Lung Diseases, National Tuberculosis and Lung Diseases Research Institute, ul. Płocka 26, 01-138 Warsaw, Poland

²

Department of Radiology, National Tuberculosis and Lung Diseases Research Institute, ul. Płocka 26, 01-138 Warsaw, Poland

³

Department od Pathology, National Tuberculosis and Lung Diseases Research Institute, ul. Płocka 26, 01-138 Warsaw, Poland

^*

Author to whom correspondence should be addressed.

Adv. Respir. Med. 2014, 82(4), 368-376; https://doi.org/10.5603/PiAP.2014.0047

Submission received: 7 January 2014 / Revised: 25 June 2014 / Accepted: 25 June 2014 / Published: 25 June 2014

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Abstract

Pulmonary involvement in the course of inflammatory bowel disease has been a subject of interest to clinicians for long time, but despite this, its epidemiology and potential pathomechanisms remain obscured. Equally unclear is the role of medications used for bowel disease treatment in lung disease development. We present three patients with ulcerative colitis, all treated with mesalazine, in whom unexplained lung disease developed. Due to different clinical and radiological presentation, different conditions were initially placed on the top of the differential list in each of them. The outcome was favourable in all patients despite differences in management. We compared our patients with similar cases from literature. We show the level of difficulty and complexity in the issue of lung disease in patients with inflammatory bowel disease.

Keywords: inflammatory bowel disease; ulcerative colitis; mesalazine; lung disease

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MDPI and ACS Style

Kacprzak, A.; Siemion-Szcześniak, I.; Szturmowicz, M.; Bestry, I.; Langfort, R.; Kuś, J. Pulmonary Pathology in Patients with Ulcerative Colitis Treated with Mesalazine—A Challenging and Complex Diagnostic Problem. Case Series and Literature Review. Adv. Respir. Med. 2014, 82, 368-376. https://doi.org/10.5603/PiAP.2014.0047

AMA Style

Kacprzak A, Siemion-Szcześniak I, Szturmowicz M, Bestry I, Langfort R, Kuś J. Pulmonary Pathology in Patients with Ulcerative Colitis Treated with Mesalazine—A Challenging and Complex Diagnostic Problem. Case Series and Literature Review. Advances in Respiratory Medicine. 2014; 82(4):368-376. https://doi.org/10.5603/PiAP.2014.0047

Chicago/Turabian Style

Kacprzak, Aneta, Izabela Siemion-Szcześniak, Monika Szturmowicz, Iwona Bestry, Renata Langfort, and Jan Kuś. 2014. "Pulmonary Pathology in Patients with Ulcerative Colitis Treated with Mesalazine—A Challenging and Complex Diagnostic Problem. Case Series and Literature Review" Advances in Respiratory Medicine 82, no. 4: 368-376. https://doi.org/10.5603/PiAP.2014.0047

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Pulmonary Pathology in Patients with Ulcerative Colitis Treated with Mesalazine—A Challenging and Complex Diagnostic Problem. Case Series and Literature Review

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