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Guidelines

Small-Cell Lung Cancer Diagnostic and Therapeutic Recommendations of Polish Lung Cancer Group

by
Maciej Krzakowski
1,*,
Tadeusz Orłowski
2,
Kazimierz Roszkowski
2,
Marian Reinfuss
3,
Włodzimierz Olszewski
1,
Rodryg Ramlau
4,
Dariusz Kowalski
1,
Krzysztof Konopa
5,
Jacek Jassem
5,
Renata Jankowska
6,
Jerzy Kozielski
7,
Marek Wojtukiewicz
8,
Kazimierz Drosik
9 and
Piotr Koralewski
10
1
Klinika Nowotworów Płuca i Klatki Piersiowej, Centrum Onkologii—Instytut im. M. Skłodowskiej-Curie, ul. Rentgena 5, 02-781 Warszawa, Poland
2
Instytut Chorób Płuc i Gruźlicy w Warszawie, 02-781 Warszawa, Poland
3
Centrum Onkologii-Instytut w Krakowie, Krakowie, Poland
4
Wielkopolskie Centrum Chorób Płuc i Gruźlicy w Poznaniu, Poznaniu, Poland
5
Akademia Medyczna w Gdańsku, Gdańsku, Poland
6
Akademia Medyczna we Wrocławiu, Wrocławiu, Poland
7
Akademia Medyczna w Zabrzu, Zabrzu, Poland
8
Akademia Medyczna w Białymstoku, Białymstoku, Poland
9
Wojewódzki Ośrodek Onkologii w Opolu, Opolu, Poland
10
Wojewódzki Szpital Specjalistyczny w Krakowie, Krakowie, Poland
*
Author to whom correspondence should be addressed.
Adv. Respir. Med. 2007, 75(1), 88-94; https://doi.org/10.5603/ARM.28015
Submission received: 31 January 2007 / Revised: 13 April 2007 / Accepted: 13 April 2007 / Published: 13 April 2007

Abstract

Small-cell lung cancer is characterized by an aggressive clinical course with high tendency for early dissemination. At presentation, patients are usually symptomatic and with hilar or mediastinal mass at radiography. Staging should be focused on identifying any evidence of distant spread. Chemotherapy including cisplatin and etoposide is a cornerstone of treatment for all patients. Limited-stage disease should be managed by chemotherapy combined with concurrent chest irradiation. All patients who achieve complete response should be considered for elective cranial irradiation. Surgical treatment may be used in highly selected patients with TNM stage I disease, and surgery should always be combined with chemotherapy. Extensive-stage disease should be managed by multi-agent chemotherapy alone. Long-term survivorus should undergo careful monitoring for development of a second primary tumour.
Keywords: small-cell lung cancer; diagnosis; staging; recommendations; chemotherapy; radiotherapy; surgical treatment small-cell lung cancer; diagnosis; staging; recommendations; chemotherapy; radiotherapy; surgical treatment

Share and Cite

MDPI and ACS Style

Krzakowski, M.; Orłowski, T.; Roszkowski, K.; Reinfuss, M.; Olszewski, W.; Ramlau, R.; Kowalski, D.; Konopa, K.; Jassem, J.; Jankowska, R.; et al. Small-Cell Lung Cancer Diagnostic and Therapeutic Recommendations of Polish Lung Cancer Group. Adv. Respir. Med. 2007, 75, 88-94. https://doi.org/10.5603/ARM.28015

AMA Style

Krzakowski M, Orłowski T, Roszkowski K, Reinfuss M, Olszewski W, Ramlau R, Kowalski D, Konopa K, Jassem J, Jankowska R, et al. Small-Cell Lung Cancer Diagnostic and Therapeutic Recommendations of Polish Lung Cancer Group. Advances in Respiratory Medicine. 2007; 75(1):88-94. https://doi.org/10.5603/ARM.28015

Chicago/Turabian Style

Krzakowski, Maciej, Tadeusz Orłowski, Kazimierz Roszkowski, Marian Reinfuss, Włodzimierz Olszewski, Rodryg Ramlau, Dariusz Kowalski, Krzysztof Konopa, Jacek Jassem, Renata Jankowska, and et al. 2007. "Small-Cell Lung Cancer Diagnostic and Therapeutic Recommendations of Polish Lung Cancer Group" Advances in Respiratory Medicine 75, no. 1: 88-94. https://doi.org/10.5603/ARM.28015

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