Comparative Anti-Inflammatory Activity of Aril Extracts of Punica granatum Fruits ^†

A substanceor treatment with an anti-inflammatory propertyis one that reduces inflammation or swelling. The main objective of this study is to evaluate the anti-inflammatory activity of pomegranate aril extract on rat paw. The anti-inflammatory activity of pomegranate was tested on rats by employing the induced carrageenan rat paw edema method. Various concentrations of the arils and the aril mixture (1:1) were prepared by dissolving in hydroalcohol and alcohol to obtain final concentrations of 100 mg/kg, 200 mg/kg, and 400 mg/kg to betested against the organisms. The effectivity of granatin B inaqueous and alcoholic extracts of the arils of Punica granatum was calculated by measuring the increase in paw volume and the percent of inhibition by comparing with the control and the standard drug.