Gelatin–Chitosan Hydrogel Biological, Antimicrobial and Mechanical Properties for Dental Applications
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials and Equipment
2.2. Gelatin–Chitosan Hydrogel Preparation
2.3. Hydrolytic and Enzymatic Degradation
2.4. Gelatin–Chitosan Hydrogel Characterization Using FTIR
2.5. Gelatin–Chitosan Hydrogel Swelling
2.6. SCAPs Cell Culture and Characterization
2.7. Gelatin–Chitosan Hydrogel SCAPs Interaction and Proliferation
2.8. Antimicrobial Activity of Gelatin–Chitosan Hydrogels
2.9. Gelatin–Chitosan Hydrogel Uniaxial Tensile Strength (UTS)
2.10. Statistical Analysis
3. Results
3.1. Degradation of the Gelatin–Chitosan Hydrogels
3.2. Gelatin–Chitosan Hydrogel Characterization Using FTIR
3.3. Gelatin–Chitosan Hydrogel Swelling Capacity
3.4. SCAPs Characterization
3.5. Gelatin–Chitosan Hydrogel SCAPs Interaction and Proliferation
3.6. Gelatin–Chitosan Hydrogel Antibacterial Effect
3.7. Gelatin–Chitosan Hydrogel Uniaxial Tensile Strength (UTS)
4. Discussion
4.1. Gelatin–Chitosan Hydrogel Preparation
4.2. Gelatin–Chitosan Hydrogel Degradation
4.3. Gelatin–Chitosan Hydrogel Characterization Using FTIR
4.4. Gelatin–Chitosan Hydrogel Swelling Capacity
4.5. SCAPs Characterization
4.6. Gelatin–Chitosan Hydrogel SCAPs Interaction and Proliferation
4.7. Gelatin–Chitosan Hydrogel Antimicrobial Effect
4.8. Gelatin–Chitosan Hydrogel Uniaxial Tensile Strength
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Flores-Espinoza, A.I.; Garcia-Contreras, R.; Guzman-Rocha, D.A.; Aranda-Herrera, B.; Chavez-Granados, P.A.; Jurado, C.A.; Alfawaz, Y.F.; Alshabib, A. Gelatin–Chitosan Hydrogel Biological, Antimicrobial and Mechanical Properties for Dental Applications. Biomimetics 2023, 8, 575. https://doi.org/10.3390/biomimetics8080575
Flores-Espinoza AI, Garcia-Contreras R, Guzman-Rocha DA, Aranda-Herrera B, Chavez-Granados PA, Jurado CA, Alfawaz YF, Alshabib A. Gelatin–Chitosan Hydrogel Biological, Antimicrobial and Mechanical Properties for Dental Applications. Biomimetics. 2023; 8(8):575. https://doi.org/10.3390/biomimetics8080575
Chicago/Turabian StyleFlores-Espinoza, Andrea Itzamantul, Rene Garcia-Contreras, Dulce Araceli Guzman-Rocha, Benjamin Aranda-Herrera, Patricia Alejandra Chavez-Granados, Carlos A. Jurado, Yasser F. Alfawaz, and Abdulrahman Alshabib. 2023. "Gelatin–Chitosan Hydrogel Biological, Antimicrobial and Mechanical Properties for Dental Applications" Biomimetics 8, no. 8: 575. https://doi.org/10.3390/biomimetics8080575