Yeast-Mediated Biomass Valorization for Biofuel Production: A Literature Review
Abstract
:1. Introduction
2. The Application of Yeast for Bioethanol Production
2.1. The Selection of Yeast Strains
2.2. Yeasts from Extreme Environments
2.3. Simultaneous Saccharification and Fermentation (SSF)
2.4. Consolidated Bioprocessing (CBP)
2.5. Metabolic and Evolutionary Engineering
3. The Application of Yeast for Biodiesel Production
3.1. The Selection of Yeast Strains
3.2. Cultivation of Yeast for Lipid Production and Transesterification
3.2.1. Submerged Fermentation
3.2.2. Solid-State Fermentation
3.2.3. Two-Stage Fermentation
3.2.4. Co-Culture System
3.3. Genetic Engineering of Yeast Strains
3.4. Characteristics of the Biodiesel Produced from Yeast Lipids
3.4.1. Cetane Number
3.4.2. Density
3.4.3. Viscosity
3.4.4. Chemical Composition
3.4.5. Calorific Value
4. Application of Yeast for Biogas and Bio-Methane Production
4.1. Biogas Production from Waste Biomass
4.2. Yeast Biomass as Feed and Biocatalysts
5. Challenges for Yeast-Mediated Biofuel Production from Waste Feedstock
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Organism | Strategy for Enhancing Biomass Utilization or Biofuel Production | Refs. |
---|---|---|
Hansenula polymorpha, Kluyveromyces lactis, Pichia pastoris, Yarrowia lipolytica | CRISPR-Cas enhancing biofuel production in non-conventional yeast | [30] |
Saccharomyces cerevisiae | CRISPR/Cas9 for application in CBP | [31] |
Saccharomyces cerevisiae | Engineering yeast for xylose utilization and ethanol production | [32] |
Zymomonas mobilis | Metabolic engineering to broaden substrate range, remove competing pathways, and enhance tolerance to ethanol and lignocellulosic hydrolysate inhibitors | [33] |
S. cerevisiae | Mining and identification of regulatory elements of bioethanol synthesis pathways, such as non-coding RNAs | [34] |
S. cerevisiae | Genetic engineering, heterologous expression of cellulase genes, xylose transporters, knock-out, and the overexpression of key genes and promoters may be closely related to bioethanol yield | [35] |
S. cerevisiae | Direction design optimization based on machine learning can effectively regulate the pretreatment parameters | [36] |
S. cerevisiae | Improving ethanol yield via the addition of quorum-sensing molecules that deter growth of S. cerevisiae cells | [37] |
Saccharomyces cerevisiae, Pichia stipitis | Metabolic engineering for enhanced bioethanol production | [38] |
S. cerevisiae extract | Constructing a cell-free system using Synthetic Biology tools | [39] |
Yarrowia lipolytica | Overexpression of Diacylglycerol acyltransferases the I (DGA) gene(s) to promote lipid accumulation | [40] |
Rhodosporidium toruloides | Overexpressing malic enzyme and acetyl-CoA carboxylase to redirect central C metabolism to enhance the availability of precursors toward lipogenic activity | [40] |
Y. lipolytica | Co-overexpressing the glyceraldehyde-3-phosphate dehydrogenase and malate dehydrogenase for increasing lipid accumulation | [40] |
Y. lipolytica | The overexpression of aldehyde dehydrogenase endogenous genes to enhance the conversion of furfural to furoic acid | [40] |
R. toruloides L1–1 | Breeding strategy to improve lipid accumulation along with stress tolerance | [40] |
Y. lipolytica | Elimination of lipid catabolism by deleting lipid-assimilating genes, e.g., the acyl-CoA oxidases (POX) or peroxisomal biogenesis (PEX) genes | [40] |
Role | Yeast/Source | Operating Conditions | Effect/Yield | Ref. |
---|---|---|---|---|
Biocatalyst | Saccharomyces cerevisiae (Yea-Sacc 1026, Alltech Inc., Nicholasville, KY, USA) | In vivo model of Jersey cows (Addition of NO3− (electron acceptor) and live yeast culture) | Methane production reduced from 22.6 mol/day to 18.8 mol/days | [107] |
Co-substrate | Bakers’ yeast and craft yeast Saccharomyces cerevisiae (Brewery in Asheville, NC, USA) | In vitro fermentation; 10 mL rumen fluid mixture with cell suspension buffer was mixed with culture media (cornmeal and silage feed) inoculated with yeast at 39 °C in a CO2 environment | Baker’s yeast: 4760 ppm Craft yeast: 3530 ppm Bakers’ + craft yeast: 3880 ppm | [108] |
Biocatalysts | Yeast isolate 1 (Commercial probiotic; Angela yeast Co., Guangzhou, China) S. cerevisiae YST2 (Bakery; Kuala Lumpur, Malaysia) | In vitro fermentation Large intestinal content as inoculum with freeze-dried yeast powder is inoculated in fermentation medium at 39 °C for 24 h | Methane production reduction potential >25% | [109] |
Biocatalyst | S. cerevisiae | Food waste anaerobic digestion. Food waste, sludge, and yeast at 37 °C, 60 rpm | Biogas production increased by 33.2% | [86] |
Source of enzyme for waste pretreatment | Enzyme mixture from Candida rogusa | Simultaneous hydrolysis and the anaerobic digestion of lipid-rich waste water from the dairy industry Enzymatic hydrolysis with lipase + Fungal enzymatic mixture 0.05 w/v | Methane yield increased by 140% | [110] |
Co-biocatalyst | Saccharomyces cerevisiae (Ragi) | Tofu wastewater; pH 8; 1 atm pressure; rumen fluid as inoculum | 421 mL | [100] |
Co-substrate | Brewer’s yeast | Wastewater Biosolids + brewer’s yeast; sewage sludge inoculum; period of 21 days at 37 °C | 338.2 NmL CH4/g volatile solids (VS) | [110] |
110Substrate | Yeast (local brewery) | Expanded granular sludge as inoculum. Temp 35 °C; pH 6.5 | Specific biogas productivity 0.430 m3/kg | [103] |
Co-biocatalyst | Meyerozyma gullerimondi (rhizosphere) | Providencia rettgeri and Meyerozyma gullerimondi (6 × 104 colonies/mL) | Methane content 63.81% | [112] |
Co-catalyst | S. cerevisiae D2 | Simultaneous saccharification and fermentation Step 1: alcoholic fermentation for 72 h Step 2: fermentation substrate + methane bacteria at 37 °C | Ethanol 16.98 ± 0.00 g/L Biogas 330 L/kg dry organic matter | [113] |
Catalyst | Yeast | Case 1: 2 g yeast + 4 g coconut fibre Case 2: 2 g yeast + 4 g cocoa pods Case 3: 2 g yeast + 4 g maize husk Case 4: 2 g yeast + 4 g orange peels Case 5: 2 g yeast + 4 g pineapple peels Period: 12 days | Maize + yeast: 23.33 mL | [114] |
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Ahuja, V.; Arora, A.; Chauhan, S.; Thakur, S.; Jeyaseelan, C.; Paul, D. Yeast-Mediated Biomass Valorization for Biofuel Production: A Literature Review. Fermentation 2023, 9, 784. https://doi.org/10.3390/fermentation9090784
Ahuja V, Arora A, Chauhan S, Thakur S, Jeyaseelan C, Paul D. Yeast-Mediated Biomass Valorization for Biofuel Production: A Literature Review. Fermentation. 2023; 9(9):784. https://doi.org/10.3390/fermentation9090784
Chicago/Turabian StyleAhuja, Vishal, Anju Arora, Shikha Chauhan, Sheetal Thakur, Christine Jeyaseelan, and Debarati Paul. 2023. "Yeast-Mediated Biomass Valorization for Biofuel Production: A Literature Review" Fermentation 9, no. 9: 784. https://doi.org/10.3390/fermentation9090784