Studies of Potential Migration of Hazardous Chemicals from Sustainable Food Contact Materials
Abstract
:1. Introduction
- (a)
- Temperature and contact duration;
- (b)
- Nature and chemical–physical characteristics of the material in contact with the food;
- (c)
- Nature of the food that interacts with the container [7].
2. Materials and Methods
2.1. Chemicals and Standards
2.2. Materials
2.3. Samples
2.4. Instruments
2.5. Calibration Curves, Linearity, Limit of Detection and Limit of Quantification
2.6. Extraction Protocol for the Total Amount of Contaminants
2.7. Migration Tests
3. Results
3.1. Steps of the Work
- Optimization of the detection and quantification method for PFASs by HPLC-ESI-Qtrap;
- Construction of calibration curves and determination of the main method validation parameters for PFASs (LOD and LOQ, linearity and inter- and intra-day repeatability);
- Evaluation of the total content of contaminants and migration of OPEs and PFASs in seven samples of biodegradable, compostable or recyclable BBFCMs.
3.1.1. Mass Spectrometric Parameters for PFASs
3.1.2. Data Quality for PFASs
3.1.3. Total Content of Contaminants and Their Migration from Investigated BBFCMs
Total Content of Contaminants
Migration of Contaminants
3.2. OPE Migration
3.3. PFAS Migration
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Stark, N.M.; Matuana, L.M. Trends in sustainable biobased packaging materials: A mini review. Mater. Today Sustain. 2021, 15, 100084. [Google Scholar] [CrossRef]
- Wang, J.; Euring, M.; Ostendorf, K.; Zhang, K. Biobased materials for food packaging. J. Bioresour. Bioprod. 2022, 7, 1–13. [Google Scholar] [CrossRef]
- Donkor, L.; Kontoh, G.; Yaya, A.; Bediako, J.K.; Apalangya, V. Bio-based and sustainable food packaging systems: Relevance, challenges, and prospects. Appl. Food Res. 2023, 3, 100356. [Google Scholar] [CrossRef]
- Ramesh, M.; Palanikumar, K.; Reddy, K.H. Plant fibre based bio-composites: Sustainable and renewable green materials. Renew. Sustain. Energy Rev. 2017, 79, 558–584. [Google Scholar] [CrossRef]
- European Commission Regulation. (EC) 1935/2004 of the European Parliament and of the Council of 27 October 2004 on materials and articles intended to come into contact with food and repealing Directives 80/590/EEC and 89/109/EEC. OJ L 2004, 338, 4–17. [Google Scholar]
- Muncke, J.; Andersson, A.M.; Backhaus, T.; Boucher, J.M.; Carney Almroth, B.; Castillo Castillo, A.; Chevrier, J.; Demeneix, B.A.; Emmanuel, J.A.; Fini, J.B.; et al. Impacts of food contact chemicals on human health: A consensus statement. Environ. Health 2020, 19, 1–12. [Google Scholar] [CrossRef] [PubMed]
- Alamri, M.S.; Qasem, A.A.; Mohamed, A.A.; Hussain, S.; Ibraheem, M.A.; Shamlan, G.; Alqah, H.A.; Qasha, A.S. Food packaging’s materials: A food safety perspective. Saudi J. Biol. Sci. 2021, 28, 4490–4499. [Google Scholar] [CrossRef] [PubMed]
- European Commission Regulation. (EU) 10/2011 of 14 January 2011 on plastic materials and articles intended to come into contact with food (Text with EEA relevance). OJ L 2011, 12, 1–89. [Google Scholar]
- Nerín, C.; Bourdoux, S.; Faust, B.; Gude, T.; Lesueur, C.; Simat, T.; Stoermer, A.; Hoek, V.E.; Oldring, P. Guidance in selecting analytical techniques for identification and quantification of non-intentionally added substances (NIAS) in food contact materials (FCMS). Food Addit. Contam. Part A 2022, 39, 620–643. [Google Scholar] [CrossRef] [PubMed]
- Sapozhnikova, Y.; Nuñez, A. Non-targeted analysis with liquid chromatography-high resolution mass spectrometry for the identification of food packaging migrants. J. Chromatogr. A 2022, 1676, 463215. [Google Scholar] [CrossRef] [PubMed]
- European Commission Recommendation. (EU) 2019/794 of 15 May 2019 on a Coordinated Control Plan with a View to Establishing the Prevalence of Certain Substances Migrating from Materials and Articles Intended to Come into Contact with Food. OJ L 2019, 129, 37–42. [Google Scholar]
- European Commission Regulation. (EU) 2017/1000 of 13 June 2017 amending annex XVII to regulation (EC) no 1907/2006 of the European Parliament and of the Council concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) as regard perfluorooctanoic acid (PFOA), its salts and PFOA-related substances (Text with EEA relevance). OJ L 2017, 150, 14–18. [Google Scholar]
- Annex XV Restriction Proposals Received by ECHA. Restriction on the Manufacture, Placing on the Market and Use of PFASs. 15 July 2021. Available online: https://echa.europa.eu/it/registry-of-restriction-intentions/-/dislist/details/0b0236e18663449b (accessed on 7 January 2024).
- Sonego, E.; Di Filippo, P.; Riccardi, C.; Pomata, D.; Bannò, A.; Simonetti, G.; Buiarelli, F. Occurrence and migration study of chemicals from baking paper and aluminium foil. Food Chem. 2023, 409, 135260. [Google Scholar] [CrossRef] [PubMed]
- Simonetti, G.; Acquaviva, L.; Buiarelli, F.; Riccardi, C.; Pomata, D.; Di Filippo, P. A Survey on Bio-based Food Packaging Material About the Presence and Migration of Flame Retardants. Curr. Anal. Chem. 2023, 19, 417–427. [Google Scholar]
- Goossen, C.P.; Schattman, R.E.; MacRae, J.D. Evidence of compost contamination with per-and polyfluoroalkyl substances (PFAS) from “compostable” food serviceware. Biointerphases 2023, 18, 030501. [Google Scholar] [CrossRef] [PubMed]
- Tsochatzis, E.D. Food contact materials: Migration and analysis. challenges and limitations on identification and quantification. Molecules 2021, 26, 3232. [Google Scholar] [CrossRef] [PubMed]
- Sonego, E.; Simonetti, G.; Di Filippo, P.; Riccardi, C.; Buiarelli, F.; Fresta, A.; Olivastri, M.; Pomata, D. Characterization of organophosphate esters (OPEs) and polyfluoralkyl substances (PFASs) in settled dust in specific workplaces. Environ. Sci. Pollut. Res. 2022, 29, 52302–52316. [Google Scholar] [CrossRef] [PubMed]
- EFSA Panel on Contaminants in the Food Chain. Public Consultation on the Draft Scientific Opinion on the Risks to Human Health Related to the Presence of Perfluoroalkyl Substances in Food; European Food Safety Authority: Parma, Italy, 2020; Available online: https://www.efsa.europa.eu/en/consultations/call/public-consultation-draft-scientific-opinion-risks-human-health (accessed on 7 January 2024).
- Arnold, L.L.; Christenson, W.R.; Cano, M.; John, M.S.; Wahle, B.S.; Cohen, S.M. Tributyl phosphate effects on urine and bladder epithelium in male Sprague–Dawley rats. Fundam. Appl. Toxicol. 1997, 40, 247–255. [Google Scholar] [CrossRef] [PubMed]
- Ji, X.; Li, N.; Ma, M.; Rao, K.; Wang, Z. In vitro estrogen-disrupting effects of organophosphate flame retardants. Sci. Total Environ. 2020, 727, 138484. [Google Scholar] [CrossRef] [PubMed]
- U.S. EPA. IRIS Toxicological Review of Perfluorobutanoic Acid (PFBA) and Related Salts; EPA/635/R-22/277F; Final Report, 2022; U.S. Environmental Protection Agency: Washington, DC, USA, 2021.
Code | Food Contact Material |
---|---|
Sample 1 | Food box |
Sample 2 | Microwave tray |
Sample 3 | Plate |
Sample 4 | Cup |
Sample 5 | Baking paper A |
Sample 6 | Baking paper B |
Sample 7 | Baking paper C |
Standardized Test Conditions | ||
---|---|---|
Column 1 | Column 2 | Column 3 |
OM2 | 10 d at 40 °C | Any long-term storage at room temperature or below, including heating up to 70 °C for up to 2 h or heating up to 100 °C for up to 15 min. |
OM3 | 2 h at 70 °C | Any contact conditions that include heating up to 70 °C for up to 2 h or up to 100 °C for up to 15 min, which are not followed by long-term storage at room or refrigerated temperature. |
OM4 | 1 h at 100 °C | High-temperature applications for all types of food at temperature up to 100 °C. |
Sample 1 | Sample 2 | Sample 3 | Sample 4 | Sample 5 | Sample 6 | Sample 7 | |
---|---|---|---|---|---|---|---|
OPEs (mg/kg) | 0.04 ± 0.01 | 0.07 ± 0.01 | 0.09 ± 0.01 | 0.16 ± 0.01 | 0.26 ± 0.06 | 0.21 ± 0.01 | 0.19 ± 0.02 |
PFASs (mg/kg) | 0.14 ± 0.06 | 0.05 ± 0.04 | 0.10 ± 0.03 | 0.11 ± 0.05 | 0.17 ± 0.04 | 0.27 ± 0.05 | 0.59 ± 0.04 |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Share and Cite
Simonetti, G.; Riccardi, C.; Pomata, D.; Acquaviva, L.; Fricano, A.; Buiarelli, F.; Senofonte, M.; Di Filippo, P. Studies of Potential Migration of Hazardous Chemicals from Sustainable Food Contact Materials. Foods 2024, 13, 645. https://doi.org/10.3390/foods13050645
Simonetti G, Riccardi C, Pomata D, Acquaviva L, Fricano A, Buiarelli F, Senofonte M, Di Filippo P. Studies of Potential Migration of Hazardous Chemicals from Sustainable Food Contact Materials. Foods. 2024; 13(5):645. https://doi.org/10.3390/foods13050645
Chicago/Turabian StyleSimonetti, Giulia, Carmela Riccardi, Donatella Pomata, Luca Acquaviva, Andrea Fricano, Francesca Buiarelli, Marta Senofonte, and Patrizia Di Filippo. 2024. "Studies of Potential Migration of Hazardous Chemicals from Sustainable Food Contact Materials" Foods 13, no. 5: 645. https://doi.org/10.3390/foods13050645