Occurrence of Mineral Oil Hydrocarbons in Omega-3 Fatty Acid Dietary Supplements
Abstract
:1. Introduction
2. Materials and Methods
2.1. Samples and Sample Preparation
2.2. Chemicals
2.3. LC-GC Analyses
2.4. Method Validation
3. Results and Discussion
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Acknowledgments
Conflicts of Interest
References
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Sample N° | Composition (Oil) | Formulation | MOSH (ppm) | CV% (MOSH) | MOAH (ppm) |
---|---|---|---|---|---|
1 | Vegetable + fish | Capsule | 33.0 | 5 | <LoQ |
2 | Vegetable + fish | Capsule | 375.7 | 3 | <LoQ |
3 | Vegetable + fish | Capsule | 6.3 | 2 | <LoQ |
4 | Fish | Capsule | 43.9 | 3 | <LoQ |
5 | Fish | Capsule | 92.9 | 4 | <LoQ |
6 | Fish | Liquid | 14.4 | 8 | <LoQ |
7 | Fish | Capsule | 42.3 | 2 | 9.9 |
8 | Fish | Capsule | 2.4 | 8 | <LoQ |
9 | Fish | Capsule | 18.4 | 1 | <LoQ |
10 | Fish | Capsule | 16.3 | 1 | <LoQ |
11 | Fish | Capsule | 4.2 | 3 | <LoQ |
12 | Fish + vegetable | Capsule | 65.4 | 4 | <LoQ |
13 | Fish | Capsule | 73.5 | <1 | 6.6 |
14 | Fish + vegetable | Liquid | 3.1 | 6 | <LoQ |
15 | Fish | Capsule | 20.2 | <1 | <LoQ |
16 | Microalgae + vegetable | Liquid | 3.8 | 2 | <LoQ |
17 | Fatty acid methyl esters | Capsule | 32.8 | 1 | <LoQ |
MOSH | MOAH | |||
---|---|---|---|---|
Sample N° | C-Fraction | ppm | C-Fraction | ppm |
1 | C25–C35 C35–C40 C40–C50 | 20.9 10.3 1.8 | - | - |
2 | C16–C20 C20–C25 C25–C35 | 60.9 278.8 36.0 | - | - |
3 | C20–C25 C25–C35 | 5.3 1.0 | - | - |
4 | C25–C35 C35–C40 | 42.5 1.4 | - | - |
5 | C20–C25 C25–C35 | 13.3 79.6 | - | - |
6 | C25–C35 C35–C40 C40–C50 | 9.1 4.7 0.6 | - | - |
7 | C25–C35 C35–C40 | 41.4 0.8 | C25–C35 | 9.9 |
8 | C25–C35 | 2.4 | - | - |
9 | C25–C35 | 18.4 | - | - |
10 | C25–C35 | 16.3 | - | - |
11 | C25–C35 C35–C40 | 3.8 0.4 | - | - |
12 | C20–C25 C25–C35 C35–C40 | 6.3 55.6 3.5 | - | - |
13 | C25–C35 | 73.5 | C25–C35 | 6.6 |
14 | C25–C35 C35–C40 | 2.9 0.2 | - | - |
15 | C25–C35 C35–C40 | 19.1 1.1 | - | - |
16 | C20–C25 C25–C35 | 0.3 3.5 | - | - |
17 | C20–C25 C25–C35 C35–C40 | 0.9 31.3 0.6 | - | - |
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Arena, A.; Zoccali, M.; Trozzi, A.; Tranchida, P.Q.; Mondello, L. Occurrence of Mineral Oil Hydrocarbons in Omega-3 Fatty Acid Dietary Supplements. Foods 2021, 10, 2424. https://doi.org/10.3390/foods10102424
Arena A, Zoccali M, Trozzi A, Tranchida PQ, Mondello L. Occurrence of Mineral Oil Hydrocarbons in Omega-3 Fatty Acid Dietary Supplements. Foods. 2021; 10(10):2424. https://doi.org/10.3390/foods10102424
Chicago/Turabian StyleArena, Alessia, Mariosimone Zoccali, Alessandra Trozzi, Peter Q. Tranchida, and Luigi Mondello. 2021. "Occurrence of Mineral Oil Hydrocarbons in Omega-3 Fatty Acid Dietary Supplements" Foods 10, no. 10: 2424. https://doi.org/10.3390/foods10102424