Peer-Review Record
Post-Hypoxic Myoclonus Status following Out-of-Hospital Cardiac Arrest—Does It still Predict a Poor Outcome? A Retrospective Study
Healthcare 2022, 10(1), 41; https://doi.org/10.3390/healthcare10010041
by
Anne C. Brøchner 1,2,3,*, Peter Lindholm 4, Margrethe J. Jensen 4, Palle Toft 4,5, Finn L. Henriksen 5,6, Jens F. Lassen 5,6 and Søren Mikkelsen 2,3,4
Reviewer 1:
Reviewer 2:
Anonymous
Healthcare 2022, 10(1), 41; https://doi.org/10.3390/healthcare10010041
Submission received: 28 October 2021
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Revised: 19 December 2021
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Accepted: 24 December 2021
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Published: 27 December 2021
(This article belongs to the Special Issue Urgent and Acute Prehospital Care)
Round 1
Reviewer 1 Report
The design and the whole presentation of the study is very professional. The data and the results are well documented and interpreted. Just two questions have arisen in my opinion, I would like the authors to answer/to complete:
- would you like provide more data about the myoclonic group, possible differencies to non-myoclonic patients - e.g., clinical diagnoses, left ventricular ejection fraction, ...any clinical, laboratory or therapeutical characteristic you consider important; (please change the title of table 1, the data are just partially demographic)
- beyond not to give up therapy, do you reccomend any specific management of myoclonic cases?
Author Response
Please see the attachment
Author Response File: 
Author Response.docx
Reviewer 2 Report
Thanks for the oppurtunity to review this manuscript.
Authors did great job in trying to evaluate prognosis of patients with myoclonic status post OHCA.
- Multiple confounding factors can lead to improved prognosis of the patients with myoclonic status. Without accounting for these confounding factors we cannot come to conclusion that myoclonic status doesnt have poor prognosis, especially when numbers were very small.
- Authors did mention about some confounding factors - Do you have data on: what kind of arrest (shockable/unshockable), any coronary intervention performed, comorbidities prior to OHCA between status epilepticus and myoclonic status patients or myoclonic status patients and patients without myoclonic status?
- 11 patients out of 36 patients with myoclonic status survived one year: 30% survival; Please include whats survival in patients without myoclonic status? And again would be better to understand confounding factors between these 2 groups.
Author Response
Please see the attachment
Author Response File: Author Response.docx
