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Article

An Efficient, Robust, and Inexpensive Grinding Device for Herbal Samples like Cinchona Bark

by
Steen Honoré HANSEN
1,*,
Else HOLMFRED
1,
Claus CORNETT
1,
Carla MALDONADO
2 and
Nina RØNSTED
2
1
Analytical Biosciences, Dept. of Pharmacy, Fac. of Health and Med. Sci., Univ. of Copenhagen, Denmark.
2
Natural History Museum of Denmark, University of Copenhagen, Denmark.
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2015, 83(2), 369-376; https://doi.org/10.3797/scipharm.1410-14
Submission received: 20 October 2014 / Accepted: 19 February 2015 / Published: 19 February 2015

Abstract

An effective, robust, and inexpensive grinding device for the grinding of herb samples like bark and roots was developed by rebuilding a commercially available coffee grinder. The grinder was constructed to be able to provide various particle sizes, to be easy to clean, and to have a minimum of dead volume. The recovery of the sample when grinding as little as 50 mg of crude Cinchona bark was about 60%. Grinding is performed in seconds with no rise in temperature, and the grinder is easily disassembled to be cleaned. The influence of the particle size of the obtained powders on the recovery of analytes in extracts of Cinchona bark was investigated using HPLC.
Keywords: Grinding; Bark and root; Cinchona bark; HPLC Grinding; Bark and root; Cinchona bark; HPLC

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MDPI and ACS Style

HANSEN, S.H.; HOLMFRED, E.; CORNETT, C.; MALDONADO, C.; RØNSTED, N. An Efficient, Robust, and Inexpensive Grinding Device for Herbal Samples like Cinchona Bark . Sci. Pharm. 2015, 83, 369-376. https://doi.org/10.3797/scipharm.1410-14

AMA Style

HANSEN SH, HOLMFRED E, CORNETT C, MALDONADO C, RØNSTED N. An Efficient, Robust, and Inexpensive Grinding Device for Herbal Samples like Cinchona Bark . Scientia Pharmaceutica. 2015; 83(2):369-376. https://doi.org/10.3797/scipharm.1410-14

Chicago/Turabian Style

HANSEN, Steen Honoré, Else HOLMFRED, Claus CORNETT, Carla MALDONADO, and Nina RØNSTED. 2015. "An Efficient, Robust, and Inexpensive Grinding Device for Herbal Samples like Cinchona Bark " Scientia Pharmaceutica 83, no. 2: 369-376. https://doi.org/10.3797/scipharm.1410-14

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