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Abstract

Absolute Bioavailability and Metabolism of Dodeca-2E,4E,8E,10E/Z-tetraenoic acid isobutylamides (“tetraene”) after Intravenous and Oral Single Doses to Rats

1
Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, USA
2
Department of Pharmacy Practice, College of Pharmacy, University of Florida, Gainesville, Florida 32610, USA
3
Institute of Pharmaceutical Sciences, Department of Pharmacognosy, Karl-Franzens-University Graz, 8010 Graz, Austria
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2009, 77(6), 195; https://doi.org/10.3797/scipharm.oephg.21.SL-28
Submission received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009

Excerpt

Note: In lieu of an abstract, this is an excerpt from the first page.

This study assessed the absolute and relative bioavailabilities of dodeca-2E,4E,8E,10E/Z-tetraenoic acid isobutylamides (tetraene), one of the main bioactive constituents in Echinacea, administered as pure compounds or as an Echinacea purpurea root extract preparation. Ten rats received 0.75 mg/kg dodeca-2E,4E,8E,10E/Z-tetraenoic acid isobutylamides oral, pure and within 158.6 mg/kg Echinacea purpurea extract, or intravenous.[...]

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MDPI and ACS Style

WÖLKART, K.; FRYE, R.; DERENDORF, H.; BAUER, R.; BUTTERWECK, V. Absolute Bioavailability and Metabolism of Dodeca-2E,4E,8E,10E/Z-tetraenoic acid isobutylamides (“tetraene”) after Intravenous and Oral Single Doses to Rats. Sci. Pharm. 2009, 77, 195. https://doi.org/10.3797/scipharm.oephg.21.SL-28

AMA Style

WÖLKART K, FRYE R, DERENDORF H, BAUER R, BUTTERWECK V. Absolute Bioavailability and Metabolism of Dodeca-2E,4E,8E,10E/Z-tetraenoic acid isobutylamides (“tetraene”) after Intravenous and Oral Single Doses to Rats. Scientia Pharmaceutica. 2009; 77(Short Lectures (SL)):195. https://doi.org/10.3797/scipharm.oephg.21.SL-28

Chicago/Turabian Style

WÖLKART, K., R. FRYE, H. DERENDORF, R. BAUER, and V. BUTTERWECK. 2009. "Absolute Bioavailability and Metabolism of Dodeca-2E,4E,8E,10E/Z-tetraenoic acid isobutylamides (“tetraene”) after Intravenous and Oral Single Doses to Rats" Scientia Pharmaceutica 77, Short Lectures (SL): 195. https://doi.org/10.3797/scipharm.oephg.21.SL-28

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