Antiproliferative activity of selected medicinal plants of Jordan against a breast adenocarcinoma cell line (MCF7)
Abstract
From the tested crude extracts, Inula graveolens, Salvia dominica, Conyza canadiensis and Achillea santolina showed potent antiproliferative activity and the activity resided in the chloroform/ethanolic extracts. The most active plant was I. graveolens with an IC50 of 3.83 μg/ml. Phytochemical screening indicated the presence of flavonoids, terpenoids, and phenolics in all active extracts. These results indicate the possible potential use of medicinal plants from the Jordanian flora as antineoplastic agents.
Share and Cite
Abu-Dahab, R.; Afifi, F. Antiproliferative activity of selected medicinal plants of Jordan against a breast adenocarcinoma cell line (MCF7). Sci. Pharm. 2007, 75, 121-146. https://doi.org/10.3797/scipharm.2007.75.121
Abu-Dahab R, Afifi F. Antiproliferative activity of selected medicinal plants of Jordan against a breast adenocarcinoma cell line (MCF7). Scientia Pharmaceutica. 2007; 75(3):121-146. https://doi.org/10.3797/scipharm.2007.75.121
Chicago/Turabian StyleAbu-Dahab, Rana, and Fatma Afifi. 2007. "Antiproliferative activity of selected medicinal plants of Jordan against a breast adenocarcinoma cell line (MCF7)" Scientia Pharmaceutica 75, no. 3: 121-146. https://doi.org/10.3797/scipharm.2007.75.121