Zinc Oxide Nanoparticles Induce an Adverse Effect on Blood Glucose Levels Depending On the Dose and Route of Administration in Healthy and Diabetic Rats
Abstract
:1. Introduction
2. Materials and Methods
2.1. Material
2.2. ZnONPs Characterization
2.3. Animals
2.4. Experimental Design and Diabetes Induction
2.5. Evaluation of Zinc Oxide Nanoparticles on Fasting Glycemia Values
2.6. Statistics
3. Results and Discussion
4. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Virgen-Ortiz, A.; Apolinar-Iribe, A.; Díaz-Reval, I.; Parra-Delgado, H.; Limón-Miranda, S.; Sánchez-Pastor, E.A.; Castro-Sánchez, L.; Jesús Castillo, S.; Dagnino-Acosta, A.; Bonales-Alatorre, E.; et al. Zinc Oxide Nanoparticles Induce an Adverse Effect on Blood Glucose Levels Depending On the Dose and Route of Administration in Healthy and Diabetic Rats. Nanomaterials 2020, 10, 2005. https://doi.org/10.3390/nano10102005
Virgen-Ortiz A, Apolinar-Iribe A, Díaz-Reval I, Parra-Delgado H, Limón-Miranda S, Sánchez-Pastor EA, Castro-Sánchez L, Jesús Castillo S, Dagnino-Acosta A, Bonales-Alatorre E, et al. Zinc Oxide Nanoparticles Induce an Adverse Effect on Blood Glucose Levels Depending On the Dose and Route of Administration in Healthy and Diabetic Rats. Nanomaterials. 2020; 10(10):2005. https://doi.org/10.3390/nano10102005
Chicago/Turabian StyleVirgen-Ortiz, Adolfo, Alejandro Apolinar-Iribe, Irene Díaz-Reval, Hortensia Parra-Delgado, Saraí Limón-Miranda, Enrique Alejandro Sánchez-Pastor, Luis Castro-Sánchez, Santos Jesús Castillo, Adan Dagnino-Acosta, Edgar Bonales-Alatorre, and et al. 2020. "Zinc Oxide Nanoparticles Induce an Adverse Effect on Blood Glucose Levels Depending On the Dose and Route of Administration in Healthy and Diabetic Rats" Nanomaterials 10, no. 10: 2005. https://doi.org/10.3390/nano10102005