Should We Stop Collecting the Preoperative Autologous Blood before Bone Marrow Harvest?
Abstract
:1. Introduction
2. Donors and Methods
Statistics
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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All Donors | Male | Female | p | |
---|---|---|---|---|
Number of donors | 216 | 160 | 56 | na |
Males/females | 100% | 74% | 26% | na |
Age (years) | 32 (19–63) | 32 (19–63) | 29 (19–47) | ns |
Weight (kg) | 82 (50–131) | 86 (63–131) | 65 (50–100) | p < 0.0001 |
Bone marrow harvest volume (mL) | 1170 (445–1350) | 1295 (445–1350) | 1100 (450–1350) | p = 0.015 |
Marrow volume/kg donor (mL) | 15 (4–20) | 14 (4–20) | 17 (8–20) | p < 0.0001 |
Collected TNC/kg patient (×106/kg) | 347 (124–1971) | 362 (156–1625) | 307 (124–1971) | ns |
All Donors | Male | Female | p | |
---|---|---|---|---|
Hb at work-up (g/L) | 149 (103–175) | 153 (103–175) | 135 (112–152) | p < 0.0001 |
Hb day before BM harvest (g/L) | 141 (100–168) | 153 (127–175) | 126 (100–139) | p < 0.0001 |
Hb decrease after PAD collection (g/L) | 8 (0–34) | 8 (0–34) | 9 (0–30) | ns |
Hb after BM (AT yes *) (g/L); 111 donors | 111 (86–145) | 116 (95–145) | 100 (86–118) | p < 0.0001 |
Hb after BM (AT no) (g/L); 67 donors | 124 (103–146) | 125 (111–146) | 106 (103–113) | p = 0.0001 |
Hb decrease after BM collection (g/L) | 23 (4–56) | 23 (4–56) | 25 (4–50) | ns |
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Lysák, D.; Hejretová, L.; Hrabětová, M.; Jindra, P. Should We Stop Collecting the Preoperative Autologous Blood before Bone Marrow Harvest? J. Clin. Med. 2021, 10, 2134. https://doi.org/10.3390/jcm10102134
Lysák D, Hejretová L, Hrabětová M, Jindra P. Should We Stop Collecting the Preoperative Autologous Blood before Bone Marrow Harvest? Journal of Clinical Medicine. 2021; 10(10):2134. https://doi.org/10.3390/jcm10102134
Chicago/Turabian StyleLysák, Daniel, Lenka Hejretová, Marcela Hrabětová, and Pavel Jindra. 2021. "Should We Stop Collecting the Preoperative Autologous Blood before Bone Marrow Harvest?" Journal of Clinical Medicine 10, no. 10: 2134. https://doi.org/10.3390/jcm10102134