Prefrontal Cerebral Oxygenated Hemoglobin Concentration during the Category Fluency and Finger-Tapping Tasks in Adults with and without Mild Cognitive Impairment: A Near-Infrared Spectroscopy Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Participants and Methods
2.2. Category Fluency Task
2.3. Finger-Tapping Task
2.4. Dual Task
2.5. Near-Infrared Spectroscopy
2.6. Data Analysis and Statistics
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Young Control Group (n = 30) | Elderly Participants without MCI (n = 41) | Elderly Participants with MCI (n = 61) | F Value | |
---|---|---|---|---|
Age (years) | 20.9 ± 0.7 | 74.4 ± 7.1 | 78.2 ± 6.4 | 433.6 *** |
Sex (M/F) | 14:16 | 9:32 | 19:42 | |
MoCA total score (/30) | --- | 27.5 ± 1.3 | 21.6 ± 3.1 | |
Category fluency task performance | 7.4 ± 1.3 (7.0–7.9) | 6.1 ± 1.8 (5.6–6.5) | 4.7 ± 2.1 (4.2–5.2) | 21.794 *** |
Finger-tapping performance (count) | 47.9 ± 9.9 (44.2–51.6) | 32.2 ± 11.3 (28.6–35.8) | 26.0 ± 11.0 (23.3–29) | 40.669 *** |
Category fluency task performance (dual task) | 7.0 ± 1.2 (6.6–7.5) | 5.8 ± 2.1 (5.2–6.5) | 4.5 ± 2.0 (3.9–5.0) | 19.605 *** |
Finger-tapping performance (dual task) | 19.7 ± 7.8 (23.3–29.0) | 24.5 ± 9.6 (21.4–27.5) | 37.4 ± 11.1 (33.2–41.5) | 37.339 *** |
AUC (Elderly Participants with MCI/Young Control Group) (95% CI) | AUC (Elderly Participants with MCI/without MCI) (95% CI) | |
---|---|---|
Right channel during the category fluency task | 0.512 (0.375–0.649) | 0.496 (0.381–0.611) |
Left channel during the category fluency task | 0.434 (0.296–0.573) | 0.469 (0.350–0.587) |
Right channel during the dual task | 0.507 (0.378–0.636) | 0.570 (0.457–0.684) |
Left channel during the dual task | 0.499 (0.361–0.638) | 0.463 (0.345–0.582) |
Right channel during the finger-tapping task | 0.607 (0.476–0.737) | 0.411 (0.297–0.524) |
Left channel during the finger-tapping task | 0.641 (0.511–0.771) | 0.483 (0.368–0.598) |
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Takahashi, S.; Tomita, Y.; Tanaka, S.; Sakurai, N.; Kodama, N. Prefrontal Cerebral Oxygenated Hemoglobin Concentration during the Category Fluency and Finger-Tapping Tasks in Adults with and without Mild Cognitive Impairment: A Near-Infrared Spectroscopy Study. Brain Sci. 2022, 12, 1636. https://doi.org/10.3390/brainsci12121636
Takahashi S, Tomita Y, Tanaka S, Sakurai N, Kodama N. Prefrontal Cerebral Oxygenated Hemoglobin Concentration during the Category Fluency and Finger-Tapping Tasks in Adults with and without Mild Cognitive Impairment: A Near-Infrared Spectroscopy Study. Brain Sciences. 2022; 12(12):1636. https://doi.org/10.3390/brainsci12121636
Chicago/Turabian StyleTakahashi, Shingo, Yosuke Tomita, Shigeya Tanaka, Noriko Sakurai, and Naoki Kodama. 2022. "Prefrontal Cerebral Oxygenated Hemoglobin Concentration during the Category Fluency and Finger-Tapping Tasks in Adults with and without Mild Cognitive Impairment: A Near-Infrared Spectroscopy Study" Brain Sciences 12, no. 12: 1636. https://doi.org/10.3390/brainsci12121636