Precision Medicine in Inflammatory Bowel Disease
Round 1
Reviewer 1 Report
This is an interesting and useful article.
Makes clear the challenges in the field and makes some useful suggestions about how to bring biomakers into clinical practice
Generally very good, a few mistakes here and there e.g. no for not
Just requires a minor edit
Author Response
Many thanks, for the revision and comments.
English language has been revised and corrected.
Reviewer 2 Report
Diagnostics-2552564
This article reviews the authors state that the etiological mechanisms of ulcerative colitis and Crohn's disease, which are referred to as IBD, are not fully understood and that treatment methods are still in the process of being established, resulting in inadequate treatment success rates. To improve this situation, the authors propose a new data concept called "Precision Medicine.
The authors propose that Precision Medicine, which utilizes a large amount of clinical and biological data, such as biological information and biomarkers at the level of molecular disease pathways, genetics, proteomics as well as metabolomics, with artificial intelligence and machine learning algorithms, may contribute to the prognosis of IBD and the appropriateness of treatment, which have been inadequate in the past.
It is noted that an extensive review was also conducted at the ECCO scientific workshop. It can be seen that the purpose of this review is needed, and the paper seems timely as an introduction to this Precision Medicine.
A few minor comments are listed below.
1. Line 31; …..globally0   Correct to the correct number, which appears to be a Reference.
2. Line 279-304: Follow the Instructions for Authors. Delete unnecessary parts as appropriate.
Comments for author File: Comments.pdf
Author Response
Many thanks for the comments.
Changes have been done accprdingly