Correlation between CT Value on Lung Subtraction CT and Radioactive Count on Perfusion Lung Single Photon Emission CT in Chronic Thromboembolic Pulmonary Hypertension
Abstract
:1. Introduction
2. Materials and Methods
2.1. Subjects
2.2. Image Acquisition Protocol
2.2.1. Lung Subtraction CT
2.2.2. Perfusion Lung SPECT
2.3. Fusion of Lung Subtraction CT and Perfusion Lung SPECT Images
2.4. Image Evaluation
2.5. Statistical Analysis
3. Results
3.1. Radiation Exposure
3.2. Comparison of CT Value and Radioactive Count among the Three Different Classes of Lung Perfusion
3.3. Correlations between CT Value and Radioactive Count
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Number of Patients | 47 |
---|---|
Sex | Men, 9 (19.1%); women, 38 (80.9%) |
Age (range) | 62 ± 14 years (38–83 years) |
BMI (range) | 23.6 ± 3.9 kg/m2 (15.8–33.2 kg/m2) |
WHO-FC | I (n = 2), II (n = 41), III (n = 4), IV (n = 0) |
Mean PA pressure (range) | 25.4 ± 16.8 mmHg (10–113 mmHg) |
Prior therapy | Medication only (n = 6) Medication with PEA (n = 1) Medication with BPA (n = 40) |
Noncontrast CT | CTPA | Lung Subtraction CT | Perfusion Lung SPECT | |
---|---|---|---|---|
Class 1 | −826.6 ± 40.6 | −774.8 ± 40.1 | 51.9 ± 14.5 | 250.1 ± 76.3 |
Class 2 | −848.9 ± 33.1 | −819.8 ± 34.6 | 29.1 ± 13.1 | 119.1 ± 47.9 |
Class 3 | −879.3 ± 25.8 | −867.6 ± 27.3 | 11.7 ± 9.3 | 26.5 ± 20.9 |
ρ Value | p Value | |
---|---|---|
Noncontrast CT vs. Perfusion lung SPECT | 0.38 | <0.0001 |
CTPA vs. Perfusion lung SPECT | 0.61 | <0.0001 |
Lung subtraction CT vs. Perfusion lung SPECT | 0.76 | <0.0001 |
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Kariyasu, T.; Machida, H.; Yamashiro, T.; Fukushima, K.; Koyanagi, M.; Yokoyama, K.; Nishikawa, M.; Satoh, T. Correlation between CT Value on Lung Subtraction CT and Radioactive Count on Perfusion Lung Single Photon Emission CT in Chronic Thromboembolic Pulmonary Hypertension. Diagnostics 2022, 12, 2895. https://doi.org/10.3390/diagnostics12112895
Kariyasu T, Machida H, Yamashiro T, Fukushima K, Koyanagi M, Yokoyama K, Nishikawa M, Satoh T. Correlation between CT Value on Lung Subtraction CT and Radioactive Count on Perfusion Lung Single Photon Emission CT in Chronic Thromboembolic Pulmonary Hypertension. Diagnostics. 2022; 12(11):2895. https://doi.org/10.3390/diagnostics12112895
Chicago/Turabian StyleKariyasu, Toshiya, Haruhiko Machida, Tsuneo Yamashiro, Keita Fukushima, Masamichi Koyanagi, Kenichi Yokoyama, Makiko Nishikawa, and Toru Satoh. 2022. "Correlation between CT Value on Lung Subtraction CT and Radioactive Count on Perfusion Lung Single Photon Emission CT in Chronic Thromboembolic Pulmonary Hypertension" Diagnostics 12, no. 11: 2895. https://doi.org/10.3390/diagnostics12112895