Unveiling the World of Circulating and Exosomal microRNAs in Renal Cell Carcinoma
, Vera Constâncio 1,3, João Lobo 1,4,5, Rui Henrique 1,4,5,*,†and Carmen Jerónimo 1,5,*,†Round 1
Reviewer 1 Report
Authors answered all my questions. However, I still think that the authors are not very clear on the mechanism behind microRNAs.
I recommend studying it thoroughly before writing a review.
However, also given the positive comments of the other reviewer, I think that the article can be accepted for publication.
This manuscript is a resubmission of an earlier submission. The following is a list of the peer review reports and author responses from that submission.
Round 1
Reviewer 1 Report
Sequeira et al. write a review of micro-RNA in renal cell carcinoma. Unfortunately the work is not concluded
Just for example:
- In many many micro-RNA authors didn't report the isoform (-5p, -3p)
- They never report if micro-RNA are downregulated or upregulate
- I think that authors must review the function of the micro-RNA reported.
In conclusion I think that the work is not publishable in the present state.
Reviewer 2 Report
The paper put forwards the advantage of Liquid Biopsies for cancer detection.
I found the paper to be overall concise and easy to read.
