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Peer-Review Record

Biobanking in Molecular Biomarker Research for the Early Detection of Cancer

Cancers 2020, 12(4), 776; https://doi.org/10.3390/cancers12040776
by Kim Lommen 1, Selena Odeh 1, Chiel C. de Theije 2 and Kim M. Smits 1,*
Reviewer 1: Anonymous
Cancers 2020, 12(4), 776; https://doi.org/10.3390/cancers12040776
Submission received: 9 March 2020 / Revised: 23 March 2020 / Accepted: 24 March 2020 / Published: 25 March 2020
(This article belongs to the Special Issue Non-Invasive Early Detection of Cancers)

Round 1

Reviewer 1 Report

Given the importance of biobanking, this paper is a rare and timely paper.

  1. Let's add a difference in terms of utility between general biobanking and biobanking specialized in specific diseases.
  2. Could you recommend general collection protocols in liquid biopsies in examples ?
  3. It is needed the principle of quality control  and real method.
  4. What is the maximum amount of time you can expose to room temperature?
  5. How about adding biobanking services to help researchers in other countries?

Author Response

Thank you for reviewing our manuscript and the comments provided. We have taken these into account when revising the manuscript.

Please see the attachment.

Author Response File: Author Response.docx

Reviewer 2 Report

Biobanking in molecular biomarker research for the early detection of cancer is an interesting manuscript for those interested in validating biomarkers. Nevertheless, examples regarding usefulness in the cancer area would enrich the paper. 
More illulstrative diagrams with clinical implications in sample collection and processing would improve the quality of the manuscript.

A brief description of translational medicine application of biobanks for molecular biomarkers  would attrack more readers 

Author Response

Thank you for reviewing our manuscript and the comments provided. We have taken these into account when revising the manuscript.

Please see the attachment.

Author Response File: Author Response.docx

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