Nutritional Profile, Phytochemical Compounds, Biological Activities, and Utilisation of Onion Peel for Food Applications: A Review
, Aamir Hussain Dar 1, Ravi Pandiselvam 4,*, Sobiya Manzoor 5, Shabir Ahmad Mir 6, Rafeeya Shams 7, Kshirod K. Dash 8, Ufaq Fayaz 5, Shafat Ahmad Khan 1, G. Jeevarathinam 9, Yue Zhang 10, Alexandru Vasile Rusu 11,12,* and Monica Trif 13
Round 1
Reviewer 1 Report
The study entitled “Nutritional profile, phytochemical compounds, biological activities, and utilization of onion peel for food applications: A Review” is a very interesting one that has as references a large number of bibliographic sources, numbering 71, and my suggestions are:
line 50: delete the “/”
line 58: “Phenols” are mentioned twice, please delete one word
line 69: please explain what means FAS
line 73: please explain what means dm
line 77: please add the interval for flavonoids content
lines 85-86: please check if the unit of measurement is correct
line 135: OPE means?
Lines 196-197: explain what means TPC, TFC
Line 220: explain what means COX, LOX activity
Please reorganize the Conclusion section. In my opinion it is a too brief description of the conclusions of this manuscript, I think that more data needs to be added.
Good luck!
Author Response
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line 50:
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delete the “/” |
Corrected
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line 58: |
“Phenols” are mentioned twice, please delete one word |
Corrected
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line 69 |
please explain what means FAS |
Corrected |
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line 73
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please explain what means dm |
Explained
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line 77
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please add the interval for flavonoids content |
Corrected
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lines 85-86
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please check if the unit of measurement is correct |
Checked and is appropriate |
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line 135
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OPE means? |
Explained |
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Lines 196-197
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explain what means TPC, TFC |
Explained
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Line 220
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explain what means COX, LOX activity |
Corrected |
Author Response File: 
Author Response.pdf
Reviewer 2 Report
This manuscript thoroughly reviewed the nutritional aspects of onion peel and its (possible) applications in food industry. Readers are likely to have interests in this topic for making full use of onion peel. However, there are several issues to be addressed:
Line 73: what is 8.3-15.6%？ what does "dm" stand for? Do you mean dry basis?
Page 6-13: in part 3. Therapeutic effects of Quercetin, there are too much contents on Quercetin itself. I suggest to reduce much of the content and focus on the healthy effect of onion peel.
Author Response
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S.NO. |
Reviewer 2 |
Comments |
Action taken |
|
1. |
Examples: O.E (line 203), A.O (line 205), COX (line 230), OPE (line 267, 298), AKI (line 390), etc.
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Since there are many abbreviations, and some of them are mentioned before their definition and cause a bit of confusion, then please add list of abbreviations at the end of the manuscript, before the reference list. |
Corrected
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2. |
Line 200 |
In order to broaden the knowledge about onion drying, a report about the preservation of onion by using drying (as well as the modeling of the drying process) that contributes to the lowering of the environmental impact of food waste disposal can be found here: Compaore et al, Drying Technology 35 (2017) 500-508 https://doi.org/10.1080/07373937.2016.1192189
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Corrected |
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3. |
Line 98 |
Please separate “cepa” and “onion” with a space.
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Corrected
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4. |
Line 105 |
Please write cepa with lowercase c, and in italic. |
Corrected
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5. |
Line 115: |
…phytonutrients… --> lowercase p |
Corrected
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6. |
Line 141 |
…phenolics. Cyanidine-3-glucoside… --> not cyaniDING |
Corrected
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7. |
Line 142 |
…cyanidin… --> not cyaniDING |
Corrected
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8. |
Table 3 column 2: |
Please write grape, strawberry, vegetables, lettuce, all started with lowercase letters, not uppercase letters |
Corrected
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9. |
Line 196: |
…2nd year --> superscripted nd |
Corrected
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10. |
Line 280: |
…of six different… --> not “6” |
Corrected
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11. |
Line 314 |
Allium --> in italic |
Corrected
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12. |
Line 335, 337, 340 |
Please do not write variant “O157:H7” in italic. |
Corrected
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13. |
Line 343 |
Allium fistulosum --> Write complete genus unnabreviated, because there is another species with the genus started with letter A in this manuscript, i.e. Aspergillus versicolor. |
Corrected |
|
14. |
Line 350, 351, 352, 353 |
Please write the scientific names with the genera started with S in complete unabbreviated style! There are many species in this manuscript with the genus started with letter “S.” could be Staphylococcus, Salmonella, Streptococcus, etc. |
Corrected |
|
15. |
Line 350, 353 |
In order to be consistent throughout the manuscript, please write E. coli and P. aeruginosa as Escherichia coli and Pseudomonas aeruginosa, respectively, in complete way (not abbreviated). |
Corrected |
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16. |
Line 383 |
COVID-19 --> with all uppercase letters. |
Corrected |
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17. |
Line 384-404 |
The section title (line 383) has the word “COVID-19” in it, but the paragraph does not. Next to “SARS-CoV” words in this paragraph, please also add “SARS-CoV-2/COVID-19” words |
Corrected |
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18. |
Line 432-444:
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These long sentences have no references at all. Do they come only from reference 67? If not, then please add other references related to each sentence! |
All come from same reference |
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19. |
Line 420 |
After Figure 2, suddenly Figure 4 pops out, no Figure 3. Please revise the sequence in the paragraph also. |
Corrected |
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20. |
Line 453:
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Change “Figure 5-“ as “Figure 4.”, not with a dash but with a dot. Please revise the sequence in the paragraph also |
Corrected |
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21. |
Line 455
|
Please separate “carbohydrates” and “(pectin…” with a space. |
Corrected |
|
22. |
Line 455
|
Please separate “[68].” and “Because” with a space. |
Corrected |
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23. |
Line 455 |
Please separate “[69, 70].” and “There” with a space. |
Corrected |
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24. |
Line 469 |
…in onion… --> lowercase o |
Corrected |
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25. |
Line 489
|
Ozone Sci. Eng. --> uppercase S and E, respectively |
Corrected |
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26. |
Line 496
|
Please write complete list of authors, do not shorten with multiple dots! |
Corrected |
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27. |
Line 508
|
Please write scientific names in italic! --> Allium cepa |
Corrected |
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28. |
Line 515 |
Please write scientific names in italic! --> Oncorhynchus mykiss |
Corrected |
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29. |
Line 529
|
CO2 --> subscripted 2 |
Corrected |
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30. |
Line 543
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3. Please write scientific names in italic! --> Allium cep
|
Corrected |
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31. |
Line 544
|
Please write the journal name Iran. J. Basic. Med. Sci. in italic |
Corrected |
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32. |
Line 557
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Please write scientific names in italic! --> Allium cepa |
Corrected |
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33. |
Line 558
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Please write scientific names in italic! --> Salmonella enterica typhimurium
|
Corrected |
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34. |
Line 560 |
Please write scientific names in italic! --> Allium fistulosum |
Corrected |
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35. |
Line 563
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Please write scientific names in italic! --> Blomia tropicalis |
Corrected |
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36. |
Line 566
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Please separate “-associated” and “acute” with a space |
Corrected |
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37. |
Line 615
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Please write scientific names in italic! --> Clariasgariepinus |
Corrected |
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38. |
Line 617 |
Please write scientific names in italic! --> Allium cepa |
Corrected |
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39. |
Line 630 |
Please write scientific names in italic! --> Allium cepa |
Corrected |
|
40. |
Line 632
|
Please write scientific names in italic! --> Allium cepa |
Corrected |
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41. |
Line 634 |
Please write scientific names in italic! --> Allium cepa |
Corrected |
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42. |
Line 640 |
Please write scientific names in italic! --> Allium cepa |
Corrected |
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43. |
Line 640
|
Please correct the writing of the title, many space bars are missing. |
Corrected |
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44. |
Line 640-641
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Please write the journal in italic style. |
Corrected |
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45. |
Line 643 |
To be consistent, write the journal name in ISO-abbreviated style and italic as J. Environ. Chem. Eng |
Corrected |
Reviewer 3 Report
Review of sustainability-1911243
This is a comprehensive and up-to-date review of onion from the perspective of nutrition, phytochemistry, and antimicrobial applications, accompanied with a discussion related with COVID-19. There are some issues to be corrected and added, as follows:
- Since there are many abbreviations, and some of them are mentioned before their definition and cause a bit of confusion, then please add list of abbreviations at the end of the manuscript, before the reference list. Examples: O.E (line 203), A.O (line 205), COX (line 230), OPE (line 267, 298), AKI (line 390), etc.
- Line 200: In order to broaden the knowledge about onion drying, a report about the preservation of onion by using drying (as well as the modeling of the drying process) that contributes to the lowering of the environmental impact of food waste disposal can be found here: Compaore et al, Drying Technology 35 (2017) 500-508 https://doi.org/10.1080/07373937.2016.1192189
- Line 98: Please separate “cepa” and “onion” with a space.
- Line 105: Please write cepa with lowercase c, and in italic.
- Line 115: …phytonutrients… --> lowercase p
- Line 141: …phenolics. Cyanidine-3-glucoside… --> not cyaniDING
- Line 142: …cyanidin… --> not cyaniDING
- Table 3 column 2: Please write grape, strawberry, vegetables, lettuce, all started with lowercase letters, not uppercase letters.
- Line 196: …2nd year --> superscripted nd
- Line 280: …of six different… --> not “6”
- Line 314: Allium --> in italic
- Line 335, 337, 340: Please do not write variant “O157:H7” in italic.
- Line 343: Allium fistulosum --> Write complete genus unnabreviated, because there is another species with the genus started with letter A in this manuscript, i.e. Aspergillus versicolor.
- Line 350, 351, 352, 353: Please write the scientific names with the genera started with S in complete unabbreviated style! There are many species in this manuscript with the genus started with letter “S.” could be Staphylococcus, Salmonella, Streptococcus, etc.
- Line 350, 353: In order to be consistent throughout the manuscript, please write E. coli and P. aeruginosa as Escherichia coli and Pseudomonas aeruginosa, respectively, in complete way (not abbreviated).
- Line 383: COVID-19 --> with all uppercase letters.
- Line 384-404: The section title (line 383) has the word “COVID-19” in it, but the paragraph does not. Next to “SARS-CoV” words in this paragraph, please also add “SARS-CoV-2/COVID-19” words.
- Line 432-444: These long sentences have no references at all. Do they come only from reference 67? If not, then please add other references related to each sentence!
- Line 420: After Figure 2, suddenly Figure 4 pops out, no Figure 3. Please revise the sequence in the paragraph also.
- Line 453: Change “Figure 5-“ as “Figure 4.”, not with a dash but with a dot. Please revise the sequence in the paragraph also.
- Line 455: Please separate “carbohydrates” and “(pectin…” with a space.
- Line 455: Please separate “[68].” and “Because” with a space.
- Line 455: Please separate “[69, 70].” and “There” with a space.
- Line 469: …in onion… --> lowercase o
- Line 489: Ozone Sci. Eng. --> uppercase S and E, respectively
- Line 496: Please write complete list of authors, do not shorten with multiple dots!
- Line 508: Please write scientific names in italic! --> Allium cepa
- Line 515: Please write scientific names in italic! --> Oncorhynchus mykiss
- Line 529: CO2 --> subscripted 2
- Line 543: Please write scientific names in italic! --> Allium cepa
- Line 544: Please write the journal name Iran. J. Basic. Med. Sci. in italic!
- Line 557: Please write scientific names in italic! --> Allium cepa
- Line 558: Please write scientific names in italic! --> Salmonella enterica typhimurium
- Line 560: Please write scientific names in italic! --> Allium fistulosum
- Line 563: Please write scientific names in italic! --> Blomia tropicalis
- Line 566: Please separate “-associated” and “acute” with a space
- Line 615: Please write scientific names in italic! --> Clarias gariepinus
- Line 617: Please write scientific names in italic! --> Allium cepa
- Line 630: Please write scientific names in italic! --> Allium cepa
Line 632: Please write scientific names in italic! --> Allium cepa
Line 634: Please write scientific names in italic! --> Allium cepa - Line 640: Please write scientific names in italic! --> Allium cepa
- Line 640: Please correct the writing of the title, many space bars are missing.
- Line 640-641: Please write the journal in italic style.
Line 643: To be consistent, write the journal name in ISO-abbreviated style and italic as J. Environ. Chem. Eng.
Author Response
|
S.NO. |
Reviewer 3 |
Comments |
Action taken |
|
1. |
Line 73: |
what is 8.3-15.6%？ what does "dm" stand for? Do you mean dry basis?
|
Corrected
|
|
2. |
Page 6-13: in part 3. |
Therapeutic effects of Quercetin, there are too much contents on Quercetin itself. I suggest to reduce much of the content and focus on the healthy effect of onion peel.
|
Corrected
|
Reviewer 4 Report
Authors should revised the paper and introduce the aim of the study, metodology and discussion of the results.
The methodology should help us to understand how the revision process was conducted.
Discussion should help us to do a critical analyses of the results.
Author Response
|
S.NO. |
Reviewer4 |
Comments |
Action taken |
|
1. |
|
Authors should revise the paper and introduce the aim of the study, methodology and discussion of the results.
|
Corrected
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2. |
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The methodology should help us to understand how the revision process was conducted.
|
Corrected
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|
3 |
|
Discussion should help us to do a critical analysis of the results.
|
Corrected |
Round 2
Reviewer 2 Report
accept
Author Response
|
S No. |
Reviewer Comments |
Action Taken |
|
1 |
Line 73: what is 8.3-15.6%？ what does "dm" stand for? Do you mean dry basis? |
Correction has been implemented on Line 81. |
|
2 |
Page 6-13: in part 3. Therapeutic effects of Quercetin, there are too much contents on Quercetin itself. I suggest to reduce much of the content and focus on the healthy effect of onion peel. |
As Quercetin is a dominating element of onion peel that makes it rich in anti-inflammatory, anticancer, antimicrobial and other bioactive characteristics so the content in the manuscript has been modified as per the suggestions from page number 7 to 14. |
Reviewer 3 Report
Review of sustainability-1911243-v2
The authors have addressed the issues quite well. There are some minor issues to be revised in order to make this manuscript even better, such as:
1. Line 60-64: Please use uniform type of font (Palatino Linotype)
2. There are some words not properly separated with space bars, please check again:
· Line 69: …patties in…
· Line 338: ...Allium sps…
· Line 378: …and Escherichia coli…
· Line 380: …aureus were…
· Line 622: …associated acute…
3. Table 3: mL --> lowercase m, uppercase L
4. Table 3 again: mL --> lowercase m, uppercase L
5. Table 3: …vegetable… --> lowercase v
6. Figure 3: Please remove the orange background, perhaps replace it with white color.
7. Line 578: Please revise the name of the authors, do not use all uppercase letters.
Author Response
|
S No. |
Reviewer Comments |
Action Taken |
|
1 |
Line 60-64: Please use uniform type of font (Palatino Linotype) |
Suggestions have been implemented |
|
2 |
There are some words not properly separated with space bars, please check again: · Line 69: …patties in… |
It has been corrected in Line 67 |
|
Line 338: ...Allium sps… |
It has been corrected in Line 302 |
|
|
Line 378: …and Escherichia coli… |
It has been corrected in Line 340 |
|
|
Line 380: …aureus were… |
It has been corrected in Line 342 |
|
|
Line 622: …associated acute… |
It has been corrected in Line 566 |
|
|
3 |
Table 3: mL --> lowercase m, uppercase L |
It has been revised as per recommended suggestions |
|
4 |
Table 3 again: mL --> lowercase m, uppercase L |
It has been revised as per recommended suggestions |
|
5 |
Table 3: …vegetable… --> lowercase v |
It has been revised as per recommended suggestions |
|
6 |
Figure 3: Please remove the orange background, perhaps replace it with white color. |
The image has been improvised on Line 395 |
|
7 |
Line 578: Please revise the name of the authors, do not use all uppercase letters |
Suggestions have been implemented |
Reviewer 4 Report
Proper to publish
Author Response
|
S No. |
Reviewer Comments |
Action Taken |
|
1 |
Authors should revised the paper and introduce the aim of the study, metodology and discussion of the results. |
Correction has been implemented in the introduction and conclusion. There is no methodology as it is a systematic review but necessary changes have been implemented |
|
2 |
The methodology should help us to understand how the revision process was conducted.
|
There is no methodology as it is a systematic review but necessary changes have been implemented |
|
3 |
Discussion should help us to do a critical analyses of the results. |
Conclusion has been modified accordingly on Line 443 - 453 |
