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Case Report

Take a Second Look: It's Kikuchi’s Disease! A Case Report and Review of Literature

1
Department of Immunology and Rheumatology, Hannover Medical University, Hannover, Germany
2
Department of Pathology, Hannover Medical University, Hannover, Germany
*
Author to whom correspondence should be addressed.
Clin. Pract. 2018, 8(4), 1095; https://doi.org/10.4081/cp.2018.1095
Submission received: 8 July 2018 / Revised: 8 July 2018 / Accepted: 5 December 2018 / Published: 12 December 2018

Abstract

Generalized lymphadenopathy is a common cause of concern for both patients and clinicians. Possible etiologies include infections, malignancies and autoimmune diseases. Kikuchi Fujimoto disease (KFD) is a hyperergic condition that presents with fever, lymphadenopathy and can include systemic involvement, thus being easily mistaken for the above-mentioned entities. We report the case of a previously healthy 18-year-old male who presented with a selflimiting generalized lymphadenopathy, high fevers, skin vasculitis and polyserositis. The lymph-node biopsy revealed a histiocytotic necrotizing lymphadenitis, suggestive of Kikuchi’s disease. This case emphasizes the importance of KFD in the differential diagnosis of lymphadenopathy, especially in young adults.
Keywords: Kikuchi’s disease; necrotising histiocytic lymphadenitis Kikuchi’s disease; necrotising histiocytic lymphadenitis

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MDPI and ACS Style

Joean, O.; Thiele, T.; Raap, M.; Schmidt, R.E.; Stoll, M. Take a Second Look: It's Kikuchi’s Disease! A Case Report and Review of Literature. Clin. Pract. 2018, 8, 1095. https://doi.org/10.4081/cp.2018.1095

AMA Style

Joean O, Thiele T, Raap M, Schmidt RE, Stoll M. Take a Second Look: It's Kikuchi’s Disease! A Case Report and Review of Literature. Clinics and Practice. 2018; 8(4):1095. https://doi.org/10.4081/cp.2018.1095

Chicago/Turabian Style

Joean, Oana, Thea Thiele, Mieke Raap, Reinhold E. Schmidt, and Matthias Stoll. 2018. "Take a Second Look: It's Kikuchi’s Disease! A Case Report and Review of Literature" Clinics and Practice 8, no. 4: 1095. https://doi.org/10.4081/cp.2018.1095

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